Blar i Registrations from Cristin på forfatter "Xu, Ju"

Viser treff 1-3 av 3

    • Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function 

      Ishizuka, Yuta; Mergiya, Tadiwos Feyissa; Baldinotti, Rodolfo Da Silva Mazzarini; Xu, Ju; Hallin, Erik Ingmar; Markusson, Sigurbjörn; Kursula, Petri; Bramham, Clive Raymond Evjen (Journal article; Peer reviewed, 2022)
      Activity-regulated cytoskeleton-associated (Arc) protein plays key roles in long-term synaptic plasticity, memory, and cognitive flexibility. However, an integral understanding of Arc mechanisms is lacking. Arc is proposed ...

    • High-affinity anti-Arc nanobodies provide tools for structural and functional studies 

      Markusson, Sigurbjörn; Hallin, Erik Ingmar; Bustad, Helene J.; Raasakka, Arne; Xu, Ju; Muruganandam, Gopinath; Loris, Remy; Martinez, Aurora; Bramham, Clive Raymond Evjen; Kursula, Petri (Journal article; Peer reviewed, 2022)
      Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals. However, the mechanistic ...

    • New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome 

      Tiraboschi, Ettore; Martina, Silvia; van der Ent, Wietske; Grzyb, Kamil; Gawel, Kinga; Cordero-Maldonado, Maria Lorena; Poovathingal, Suresh K.; Heintz, Sarah; Satheesh, Somisetty Venkata; Brattespe, Jarle; Xu, Ju; Suster, Maximiliano; Skupin, Alexander; Esguerra, Camila V. (Journal article; Peer reviewed, 2020)
      Abstract Objective: To pinpoint the earliest cellular defects underlying seizure onset (epileptogenic period) during perinatal brain development in a new zebrafish model of Dravet syndrome (DS) and to investigate potential ...