dc.contributor.author | Birungi, Nancy | |
dc.contributor.author | Fadnes, Lars T. | |
dc.contributor.author | Engebretsen, Ingunn M.S. | |
dc.contributor.author | Tumwine, James K. | |
dc.contributor.author | Åstrøm, Anne Nordrehaug | |
dc.date.accessioned | 2021-02-12T10:38:25Z | |
dc.date.available | 2021-02-12T10:38:25Z | |
dc.date.created | 2020-11-07T14:21:38Z | |
dc.date.issued | 2020-09-25 | |
dc.identifier.issn | 0025-7974 | |
dc.identifier.uri | https://hdl.handle.net/11250/2727685 | |
dc.description.abstract | Background: Antiretroviral therapy for HIV in sub-Saharan Africa has transformed the highly infectious virus to a stable chronic
condition, with the advent of Highly active antiretroviral therapy (HAART). The longterm effects of HAART on the oral health of children
are understudied.
Objective: To compare the effect of lopinavir-ritonavir and lamivudine on oral health indicators (dental caries, gingivitis, tooth
eruption, and oral health related quality of life) in 5 to 7 year old HIV-1 exposed uninfected children from the ANRS 12174 trial.
Methods: This study used data collected in 2017 among children aged 5 to 7 years from the Ugandan site of the ANRS 12174
randomized trial (ClinicalTrials.gov no: NCT00640263) implemented between 2009 and 2012 in Mbale district, Eastern Uganda. The
intervention was lopinavir-ritonavir or lamuvudine treatment to prevent vertical HIV-1 transmission. One hundred thirty-seven and 139
children were randomized to receive lopinavir-ritonavir or lamivudine treatment at day 7 postpartum to compare efficacy of prevention | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wolters Kluwer | en_US |
dc.rights | Navngivelse-Ikkekommersiell 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/deed.no | * |
dc.title | Antiretroviral treatment and its impact on oral health outcomes in 5 to 7 year old Ugandan children A 6 year follow-up visit from the ANRS 12174 randomized trial | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2020 the Author(s). | en_US |
dc.source.articlenumber | e22352 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1097/MD.0000000000022352 | |
dc.identifier.cristin | 1845843 | |
dc.source.journal | Medicine | en_US |
dc.source.40 | 99 | |
dc.source.14 | 39 | |
dc.identifier.citation | Medicine. 2020, 99(39),e22352 | en_US |
dc.source.volume | 99 | en_US |
dc.source.issue | 39 | en_US |