dc.contributor.author | Berg, Lars Martin | |
dc.contributor.author | Ankjell, Torun Karina Solheim | |
dc.contributor.author | Sun, Yi-Qian | |
dc.contributor.author | Trovik, Tordis A | |
dc.contributor.author | Rikardsen, Oddveig G | |
dc.contributor.author | Sjögren, Anders | |
dc.contributor.author | Moen, Ketil | |
dc.contributor.author | Hellem, Sølve | |
dc.contributor.author | Bugten, Vegard | |
dc.date.accessioned | 2021-03-04T08:35:12Z | |
dc.date.available | 2021-03-04T08:35:12Z | |
dc.date.created | 2020-07-06T10:38:35Z | |
dc.date.issued | 2020 | |
dc.Published | International Journal of Otolaryngology. 2020, . | |
dc.identifier.issn | 1687-9201 | |
dc.identifier.uri | https://hdl.handle.net/11250/2731559 | |
dc.description.abstract | In this randomized controlled trial, patients with non-severe obstructive sleep apnea (OSA) were treated with continuous positive airway pressure (CPAP) or a twin block mandibular advancement splint (MAS). The primary objective was to compare how CPAP and MAS treatments change the health-related quality of life (HRQoL) and self-reported sleep quality of patients after 12 months of treatment. In total, 104 patients were recruited: 55 were allocated to the CPAP-treatment group and 49 to the MAS-treatment group. We used the SF36 questionnaire to evaluate HRQoL and the Pittsburgh Sleep Quality Index (PSQI) to evaluate sleep quality. All patients were included in the intention-to-treat analyses. These analyses showed improvements in the SF36 physical component score (from 48.8 ± 7.6 at baseline to 50.5 ± 8.0 at follow-up, p = 0.03) in the CPAP treatment group and in the mental component score (from 44.9 ± 12.1 to 49.3 ± 9.2, p = 0.009) in the MAS treatment group. The PSQI global score improved in both the CPAP (from 7.7 ± 3.5 to 6.6 ± 2.9, p = 0.006) and the MAS (8.0 ± 3.1 to 6.1 ± 2.6, p < 0.001) treatment group. No difference was found between treatment groups in any of the SF36 scores or PSQI global score at the final follow-up (p > 0.05) in any analysis. The improvement in the SF36 vitality domain moderately correlated to the improvement in the PSQI global score in both groups (CPAP: |r| = 0.47, p < 0.001; MAS: |r| = 0.36, p = 0.01). In the MAS treatment group, we also found a weak correlation between improvements in the SF36 mental component score and PSQI global score (|r| = 0.28, p = 0.05). In conclusion, CPAP and MAS treatments lead to similar improvements in the HRQoL and self-reported sleep quality in non-severe OSA. Improvements in aspects of HRQoL seems to be moderately correlated to the self-reported sleep quality in both CPAP and MAS treatments. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Hindawi | en_US |
dc.relation.uri | https://doi.org/10.1155/2020/2856460 | |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | Søvnforstyrrelser / søvnproblemer / søvnbesvær | en_US |
dc.subject | Sleep Disorders | en_US |
dc.title | Health-Related Quality of Life and Sleep Quality after 12 Months of Treatment in Nonsevere Obstructive Sleep Apnea: A Randomized Clinical Trial with Continuous Positive Airway Pressure and Mandibular Advancement Splints | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2020 Lars M. Berg et al. | en_US |
dc.source.articlenumber | 2856460 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1155/2020/2856460 | |
dc.identifier.cristin | 1818683 | |
dc.source.journal | International Journal of Otolaryngology | en_US |
dc.subject.nsi | VDP::Otorhinolaryngologi: 755 | en_US |
dc.subject.nsi | VDP::Otolaryngology: 755 | en_US |
dc.identifier.citation | International Journal of Otolaryngology. 2020, 2856460. | en_US |