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dc.contributor.authorOlofsson, Peren_US
dc.contributor.authorAyres-de-Campos, Diogoen_US
dc.contributor.authorKessler, Jörgen_US
dc.contributor.authorTendal, Brittaen_US
dc.contributor.authorYli, Branislava Markovicen_US
dc.contributor.authorDevoe, Lawrenceen_US
dc.date.accessioned2015-08-06T12:40:57Z
dc.date.available2015-08-06T12:40:57Z
dc.date.issued2014-06
dc.identifier.issn0001-6349
dc.identifier.urihttps://hdl.handle.net/1956/10236
dc.description.abstractWe reappraised the five randomized controlled trials that compared cardiotocography plus ECG ST interval analysis (CTG+ST) vs. cardiotocography. The numbers enrolled ranged from 5681 (Dutch randomized controlled trial) to 799 (French randomized controlled trial). The Swedish randomized controlled trial (n = 5049) was the only trial adequately powered to show a difference in metabolic acidosis, and the Plymouth randomized controlled trial (n = 2434) was only powered to show a difference in operative delivery for fetal distress. There were considerable differences in study design: the French randomized controlled trial used different inclusion criteria, and the Finnish randomized controlled trial (n = 1483) used a different metabolic acidosis definition. In the CTG+ST study arms, the larger Plymouth, Swedish and Dutch trials showed lower operative delivery and metabolic acidosis rates, whereas the smaller Finnish and French trials showed minor differences in operative delivery and higher metabolic acidosis rates. We conclude that the differences in outcomes are likely due to the considerable differences in study design and size. This will enhance heterogeneity effects in any subsequent meta-analysis.en_US
dc.language.isoengeng
dc.publisherWileyeng
dc.rightsAttribution CC BY-NCeng
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/eng
dc.subjectCardiotocographyeng
dc.subjectfetal surveillanceeng
dc.subjectmetabolic acidosiseng
dc.subjectRandomized controlled trialeng
dc.subjectST analysiseng
dc.subjectmeta-analysiseng
dc.titleA critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part I: The randomized controlled trialsen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2015-08-06T12:34:26Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2014 The Authors
dc.identifier.doihttps://doi.org/10.1111/aogs.12413
dc.identifier.cristin1152387
dc.source.journalActa Obstetricia et Gynecologica Scandinavica
dc.source.4093
dc.source.146
dc.source.pagenumber556-568


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