• Estimating the discretization dependent accuracy of perfusion in coupled capillary flow measurements 

      Hanson, Erik Andreas; Sandmann, Constantin; Malyshev, Alexander; Lundervold, Arvid; Modersitzki, Jan; Hodneland, Erlend (Peer reviewed; Journal article, 2018-07-20)
      One-compartment models are widely used to quantify hemodynamic parameters such as perfusion, blood volume and mean transit time. These parameters are routinely used for clinical diagnosis and monitoring of disease development ...
    • Fully Automatic Whole-Volume Tumor Segmentation in Cervical Cancer 

      Hodneland, Erlend; Kaliyugarasan, Sathiesh Kumar; Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Andersen, Erling; Bartsch, Hauke; Smit, Noeska Natasja; Halle, Mari Kyllesø; Krakstad, Camilla; Lundervold, Alexander Selvikvåg; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022-05-11)
      Uterine cervical cancer (CC) is the most common gynecologic malignancy worldwide. Whole-volume radiomic profiling from pelvic MRI may yield prognostic markers for tailoring treatment in CC. However, radiomic profiling ...
    • Mathematics and Medicine: How mathematics, modelling and simulations can lead to better diagnosis and treatments 

      Hanson, Erik Andreas; Hodneland, Erlend; Lorentzen, Rolf Johan; Nævdal, Geir; Nordbotten, Jan Martin; Sævareid, Ove; Zanna, Antonella (Lecture Notes in Computational Science and Engineering, Chapter; Peer reviewed; Journal article, 2019)
      Starting with the discovery of X-rays by Röntgen in 1895, the progress in medical imaging has been extraordinary and immensely beneficial to diagnosis and therapy. Parallel to the increase of imaging accuracy, there is the ...
    • Modeling a 3-D multiscale blood-flow and heat-transfer framework for realistic vascular systems 

      Amare, Rohan; Hodneland, Erlend; Roberts, Jeremy A.; Bahadori, Amir A.; Eckels, Steven (Journal article; Peer reviewed, 2022)
      Modeling of biological domains and simulation of biophysical processes occurring in them can help inform medical procedures. However, when considering complex domains such as large regions of the human body, the complexities ...
    • MRI-based radiomic signatures for pretreatment prognostication in cervical cancer 

      Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Fasmer, Kristine Eldevik; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Halle, Mari Kyllesø; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2023)
      Background Accurate pretherapeutic prognostication is important for tailoring treatment in cervical cancer (CC). Purpose To investigate whether pretreatment MRI-based radiomic signatures predict disease-specific ...
    • A new framework for assessing subject-specific whole brain circulation and perfusion using MRI-based measurements and a multi-scale continuous flow model 

      Hodneland, Erlend; Hanson, Erik Andreas; Sævareid, Ove; Nævdal, Geir; Lundervold, Arvid; Solteszova, Veronika; Zanna, Antonella; Deistung, Andreas; Reichenbach, Jürgen; Nordbotten, Jan Martin (Peer reviewed; Journal article, 2019-06-25)
      A large variety of severe medical conditions involve alterations in microvascular circulation. Hence, measurements or simulation of circulation and perfusion has considerable clinical value and can be used for diagnostics, ...
    • PDE Based Algorithms for Smooth Watersheds 

      Hodneland, Erlend; Tai, Xue-Cheng; Kalisch, Henrik (Peer reviewed; Journal article, 2016-04)
      Watershed segmentation is useful for a number of image segmentation problems with a wide range of practical applications. Traditionally, the tracking of the immersion front is done by applying a fast sorting algorithm. In ...
    • Perfusion estimation using synthetic MRI-based measurements and a porous media flow model 

      Lorentzen, Rolf Johan; Nævdal, Geir; Sævareid, Ove; Hodneland, Erlend; Hanson, Erik Andreas; Munthe-Kaas, Antonella Zanna (Journal article; Peer reviewed, 2023)
      The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis ...
    • Well-posedness and discretization for a class of models for mixed-dimensional problems with high-dimensional gap 

      Hodneland, Erlend; Hu, Xiaozhe; Nordbotten, Jan Martin (Journal article; Peer reviewed, 2021)
      In this work, we show the underlying mathematical structure of mixed-dimensional models arising from the composition of graphs and continuous domains. Such models are becoming popular in applications, in particular, to ...