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dc.contributor.authorMin, Anjieen_US
dc.contributor.authorZhu, Chaoen_US
dc.contributor.authorPeng, Shupingen_US
dc.contributor.authorRajthala, Sarojen_US
dc.contributor.authorCostea, Daniela Elenaen_US
dc.contributor.authorSapkota, Dipaken_US
dc.PublishedBioMed Research International 2015, 2015:186904eng
dc.description.abstractOral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases is increasing worldwide, especially in the low-income countries, and the prognosis remains poor in spite of recent advances in the diagnostic and therapeutic modalities. MicroRNAs (miRNAs), 18–25 nucleotides long noncoding RNA molecules, have recently gained significant attention as potential regulators and biomarkers for carcinogenesis. Recent data show that several miRNAs are deregulated in OSCC, and they have either a tumor suppressive or an oncogenic role in oral carcinogenesis. This review summarizes current knowledge on the role of miRNAs as tumor promotors or tumor suppressors in OSCC development and discusses their potential value as diagnostic and prognostic markers in OSCC.en_US
dc.publisherHindawi Publishing Corporationeng
dc.rightsAttribution CC BY 3.0eng
dc.titleMicroRNAs as important players and biomarkers in oral carcinogenesisen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2015 Anjie Min et al.
dc.subject.nsiVDP::Medisinske Fag: 700en_US

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Attribution CC BY 3.0
Except where otherwise noted, this item's license is described as Attribution CC BY 3.0