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dc.contributor.authorEngjom, Tronden_US
dc.contributor.authorErchinger, Friedemann Georgen_US
dc.contributor.authorLærum, Birger Norderuden_US
dc.contributor.authorTjora, Erlingen_US
dc.contributor.authorGilja, Odd Helgeen_US
dc.contributor.authorDimcevski, Georg Gjorgjien_US
dc.PublishedPLoS ONE 2015, 10(3):e0121121eng
dc.description.abstractBackground: Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype. Methods: Patients with cystic fibrosis and a matched group of healthy controls were included. We performed transabdominal ultrasound, and recorded echo intensities of the pancreas and parenchymal characteristics according to endoscopic ultrasound based Rosemont criteria. Results: We included 39 patients and 29 healthy controls. The cystic fibrosis patients were grouped according to exocrine pancreatic function; Cystic fibrosis, insufficient (n = 20) and sufficient (n = 19). Echo intensity measures and visual score demonstrated hyper-echogenicity in the pancreas insufficient group compared to the pancreas sufficient groups (p<0.001). Ductal and parenchymal changes were not prevalent in any of the groups. Conclusion: The hyper-echoic pancreas was the most frequent ultrasonographic finding in exocrine pancreas insufficient cystic fibrosis patients. Pancreatic echo levels correlated to pancreatic phenotype.en_US
dc.rightsAttribution CC BYeng
dc.titleUltrasound echo-intensity predicts severe Pancreatic affection in cystic fibrosis patientsen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2015 The Authors
dc.subject.nsiVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Endokrinologi: 774
dc.subject.nsiVDP::Midical sciences: 700::Clinical medical sciences: 750::Endocrinology: 774
dc.subject.nsiVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Radiologi og bildediagnostikk: 763
dc.subject.nsiVDP::Midical sciences: 700::Clinical medical sciences: 750::Radiology and diagnostic imaging: 763

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