dc.contributor.author | Næsgaard, Patrycja A. | en_US |
dc.contributor.author | Pønitz, Volker | en_US |
dc.contributor.author | Aarsetøy, Hildegunn | en_US |
dc.contributor.author | Andersen, Trygve Brugger | en_US |
dc.contributor.author | Grundt, Heidi | en_US |
dc.contributor.author | Harris, William S | en_US |
dc.contributor.author | Staines, Harry | en_US |
dc.contributor.author | Nilsen, Dennis W.T. | en_US |
dc.date.accessioned | 2016-02-23T10:12:04Z | |
dc.date.available | 2016-02-23T10:12:04Z | |
dc.date.issued | 2015 | |
dc.Published | Disease Markers 2015, 2015:283178 | eng |
dc.identifier.issn | 0278-0240 | |
dc.identifier.uri | https://hdl.handle.net/1956/11293 | |
dc.description.abstract | BACKGROUND: An inverse relationship between cardiovascular risk and levels of vitamin D and omega-3 index may exist. OBJECTIVES: To evaluate the prognostic utility of serum 25-hydroxyvitamin D [25(OH)D] in 871 patients with suspected acute coronary syndrome (ACS) and to assess the seasonal correlation between 25(OH)D and the omega-3 index in 456 ACS patients from southwestern Norway. RESULTS: In the univariate analysis the hazard ratio (HR) at 2-year follow-up for all-cause mortality in the highest as compared to the lowest quartile of 25(OH)D in the total population was 0.61 (95% confidence interval (CI), 0.37-1.00), P = 0.050. At 7-year follow-up, the corresponding HR for all-cause mortality was 0.66 (95% CI, 0.49-0.90), P = 0.008, and for females alone 0.51 (95% CI, 0.32-0.83), P = 0.006. Quartile survival did not differ in the multivariable analysis, whereas 25(OH)D < 40 nM (<16 ng/mL) was found to be independently related to mortality. Seasonal differences in 25(OH)D, but not for the omega-3 index, were noted, and the two biomarkers were positively correlated, especially during winter-spring; Pearson's correlation coefficient was 0.358, P < 0.001. CONCLUSION: Vitamin D levels are related to survival, especially in females, and correlate with the omega-3 index. | en_US |
dc.language.iso | eng | eng |
dc.publisher | Hindawi | eng |
dc.rights | Attribution CC BY | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/ | eng |
dc.title | Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2015-12-31T16:24:55Z | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2015 The Authors | |
dc.identifier.doi | https://doi.org/10.1155/2015/283178 | |
dc.identifier.cristin | 1236652 | |
dc.subject.nsi | VDP::Medisinske fag: 700::Helsefag: 800::Ernæring: 811 | |
dc.subject.nsi | VDP::Midical sciences: 700::Health sciences: 800::Nutrition: 811 | |
dc.subject.nsi | VDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771 | |
dc.subject.nsi | VDP::Midical sciences: 700::Clinical medical sciences: 750::Cardiology: 771 | |