Browsing University of Bergen Library by Title
Now showing items 3467-3486 of 9843
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Fully Automatic Whole-Volume Tumor Segmentation in Cervical Cancer
(Journal article; Peer reviewed, 2022-05-11)Uterine cervical cancer (CC) is the most common gynecologic malignancy worldwide. Whole-volume radiomic profiling from pelvic MRI may yield prognostic markers for tailoring treatment in CC. However, radiomic profiling ... -
A fully coupled numerical model of thermo-hydro-mechanical processes and fracture contact mechanics in porous media
(Journal article; Peer reviewed, 2021)Various phenomena in the subsurface are characterised by the interplay between deforming structures such as fractures and coupled thermal, hydraulic and mechanical processes. Simulation of subsurface dynamics can provide ... -
A function of profilin in force generation during malaria parasite motility that is independent of actin binding
(Journal article; Peer reviewed, 2020)During transmission of malaria-causing parasites from mosquito to mammal, Plasmodium sporozoites migrate at high speed within the skin to access the bloodstream and infect the liver. This unusual gliding motility is based ... -
Functional activity level reported by an informant is an early predictor of Alzheimer’s disease
(Journal article; Peer reviewed, 2023)Background Loss of autonomy in day-to-day functioning is one of the feared outcomes of Alzheimer’s disease (AD), and relatives may have been worried by subtle behavioral changes in ordinary life situations long before these ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Journal article; Peer reviewed, 2023-01-19)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional analysis and exterior calculus on mixed-dimensional geometries
(Journal article; Peer reviewed, 2020-07-12)We are interested in differential forms on mixed-dimensional geometries, in the sense of a domain containing sets of d-dimensional manifolds, structured hierarchically so that each d-dimensional manifold is contained in ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
(Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Functional annotation of human long noncoding RNAs via molecular phenotyping
(Journal article; Peer reviewed, 2020)Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression ... -
Functional brain networks in the schizophrenia spectrum and bipolar disorder with psychosis
(Journal article; Peer reviewed, 2020)Psychotic experiences have been proposed to lie on a spectrum, ranging from subclinical experiences to treatment-resistant schizophrenia. We aimed to characterize functional connectivity and brain network characteristics ... -
Functional changes in GABA and glutamate during motor learning
(Journal article; Peer reviewed, 2023)Functional magnetic resonance spectroscopy (fMRS) of GABA at 3 T poses additional challenges compared with fMRS of other metabolites because of the difficulties of measuring GABA levels; GABA is present in the brain at ... -
Functional characterization of all-trans retinoic acid-induced differentiation factor (ATRAID)
(Journal article; Peer reviewed, 2023)All-trans retinoic acid-induced differentiation (ATRAID) factor was first identified in HL60 cells. Several mRNA isoforms exist, but the respective proteins have not been fully characterized. In transfected cells expressing ... -
Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters
(Journal article; Peer reviewed, 2022)The high-affinity/low-capacity system Slc15a2 (PepT2) is responsible for the reuptake of di/tripeptides from the renal proximal tubule, but it also operates in many other tissues and organs. Information regarding PepT2 in ... -
Functional connectome differences in individuals with hallucinations across the psychosis continuum
(Journal article; Peer reviewed, 2021)Hallucinations may arise from an imbalance between sensory and higher cognitive brain regions, reflected by alterations in functional connectivity. It is unknown whether hallucinations across the psychosis continuum exhibit ... -
Functional Data Analysis of Non-manual Marking of Questions in Kazakh-Russian Sign Language
(Chapter, 2022)This paper is a continuation of Kuznetsova et al. (2021), which described non-manual markers of polar and wh-questions in comparison with statements in an NLP dataset of Kazakh-Russian Sign Language (KRSL) using Computer ... -
Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro
(Journal article; Peer reviewed, 2021)Short‐chain 3‐hydroxyacyl‐CoA dehydrogenase (SCHAD), encoded by the HADH gene, is a ubiquitously expressed mitochondrial enzyme involved in fatty acid oxidation. This protein also plays a role in insulin secretion as ... -
Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs
(Journal article; Peer reviewed, 2023)Aquaporin-mediated oocyte hydration is considered important for the evolution of pelagic eggs and the radiative success of marine teleosts. However, the molecular regulatory mechanisms controlling this vital process are ... -
Functional inequalities on path space of sub-Riemannian manifolds and applications
(Journal article; Peer reviewed, 2021)We consider the path space of a manifold with a measure induced by a stochastic flow with an infinitesimal generator that is hypoelliptic, but not elliptic. These generators can be seen as sub-Laplacians of a sub-Riemannian ... -
Functional properties of GABAA receptors of AII amacrine cells of the rat retina
(Journal article, 2023-04-05)Amacrine cells are a highly diverse group of inhibitory retinal interneurons that sculpt the responses of bipolar cells, ganglion cells, and other amacrine cells. They integrate excitatory inputs from bipolar cells and ... -
Functional specialization of Aurora kinase homologs during oogenic meiosis in the tunicate Oikopleura dioica
(Journal article; Peer reviewed, 2023)A single Aurora kinase found in non-vertebrate deuterostomes is assumed to represent the ancestor of vertebrate Auroras A/B/C. However, the tunicate Oikopleura dioica, a member of the sister group to vertebrates, possesses ... -
Functional traits of alpine plant communities show long-term resistance to changing herbivore densities
(Journal article; Peer reviewed, 2021)Herbivores shape vegetation by suppressing certain plant species while benefitting others. By thus modifying plant species functional composition, herbivores affect carbon cycling, albedo, vegetation structure and species' ...