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dc.contributor.authorFasmer, Ole Bernten_US
dc.contributor.authorMjeldheim, Kristinen_US
dc.contributor.authorFørland, Wencheen_US
dc.contributor.authorHansen, Anita Lillen_US
dc.contributor.authorSyrstad, Vigdis Elin Giæveren_US
dc.contributor.authorØdegaard, Ketil Joachimen_US
dc.contributor.authorBerle, Jan Øysteinen_US
dc.PublishedBMC Psychiatry 2016, 16:284eng
dc.description.abstractBackground: Attention Deficit Hyperactivity Disorder (ADHD) is a heterogeneous disorder. Therefore it is important to look for factors that can contribute to better diagnosis and classification of these patients. The aims of the study were to characterize adult psychiatric out-patients with a mixture of mood, anxiety and attentional problems using an objective neuropsychological test of attention combined with an assessment of mood instability. Method: Newly referred patients (n = 99; aged 18–65 years) requiring diagnostic evaluation of ADHD, mood or anxiety disorders were recruited, and were given a comprehensive diagnostic evaluation including the self-report form of the cyclothymic temperament scale and Conner’s Continuous Performance Test II (CPT-II). In addition to the traditional measures from this test we have extracted raw data and analysed time series using linear and non-linear mathematical methods. Results: Fifty patients fulfilled criteria for ADHD, while 49 did not, and were given other psychiatric diagnoses (clinical controls). When compared to the clinical controls the ADHD patients had more omission and commission errors, and higher reaction time variability. Analyses of response times showed higher values for skewness in the ADHD patients, and lower values for sample entropy and symbolic dynamics. Among the ADHD patients 59 % fulfilled criteria for a cyclothymic temperament, and this group had higher reaction time variability and lower scores on complexity than the group without this temperament. Conclusion: The CPT-II is a useful instrument in the assessment of ADHD in adult patients. Additional information from this test was obtained by analyzing response times using linear and non-linear methods, and this showed that ADHD patients with a cyclothymic temperament were different from those without this temperament.en_US
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.subjectCyclothymic temperamenteng
dc.subjectContinuous performance testeng
dc.titleLinear and non-linear analyses of Conner’s Continuous Performance Test-II discriminate adult patients with attention deficit hyperactivity disorder from patients with mood and anxiety disordersen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright The Author(s).

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