Thyroid function among breastfed children with chronically excessive iodine intakes
Peer reviewed, Journal article
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Iodine excess may impair thyroid function and trigger adverse health consequences for children. This study aims to describe iodine status among breastfed infants with high iodine exposure in the Saharawi refugee camps Algeria, and further assess thyroid function and iodine status among the children three years later. In 2010, a cross-sectional study among 111 breastfed children aged 0–6 months was performed (baseline study). In 2013, a second cross-sectional study (follow-up study) was conducted among 289 children; 213 newly selected and 76 children retrieved from baseline. Urinary iodine concentration (UIC) and breast milk iodine concentration (BMIC) were measured at baseline. UIC, thyroid hormones and serum thyroglobulin (Tg) were measured at follow-up. At baseline and follow-up, 88% and 72% had excessive iodine intakes (UIC ≥ 300 µg/L), respectively. At follow-up, 24% had a thyroid hormone disturbance and/or elevated serum Tg, including 9% with subclinical hypothyroidism (SCH), 4% with elevated fT3 and 14% with elevated Tg. Children with SCH had poorer linear growth and were more likely to be underweight than the children without SCH. Excessive iodine intakes and thyroid disturbances were common among children below four years of age in our study. Further, SCH seemed to be associated with poor growth and weight.
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Iodine status in Norwegian preschool children and significance of dietary sources of iodine and parental socio-economic factors - A cross-sectional study Odland, Mathilde (Master thesis, 2016-05-15)Iodine is an essential trace element with important physiological effects in the human body. Iodine is necessary for thyroid hormone synthesis. The hormones are needed for tissue development in the central nervous system, ...
Urinary iodine concentration and iodine intake in pregnant Norwegian women. Results from the “Little in Norway” Study (LiN) Roldan Sanchez, Perla Vanessa (Master thesis, 2015-05-15)Background Iodine is an essential nutrient for the synthesis of thyroid hormones. Inadequate iodine intake is especially critical during pregnancy, lactation and early childhood. Iodine deficiency early in life impairs the ...
Iodine status in Norwegian preschool children and associations with dietary iodine sources: the FINS-KIDS study Nerhus, Ive; Odland, Mathilde; Kjellevold, Marian; Midtbø, Lisa Kolden; Wik, Maria; Graff, Ingvild Eide; Lie, Øyvind; Kvestad, Ingrid; Frøyland, Livar; Dahl, Lisbeth; Øyen, Jannike (Peer reviewed; Journal article, 2018)Purpose. Iodine is an essential trace element necessary for thyroid hormone synthesis. Iodine deficiency is a continuing public health problem despite international efforts to eliminate it. Studies on iodine status in ...