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dc.contributor.authorAakre, Ingeren_US
dc.contributor.authorStrand, Tor Aen_US
dc.contributor.authorBjøro, Trineen_US
dc.contributor.authorNordheim, Ingriden_US
dc.contributor.authorBarikmo, Ingriden_US
dc.contributor.authorAres, Susanaen_US
dc.contributor.authorAlcorta, Marta Duqueen_US
dc.contributor.authorHenjum, Sigrunen_US
dc.PublishedAakre I, Strand TA, Bjøro T, Nordheim I, Barikmo I, Ares, Alcorta, Henjum S. Thyroid function among breastfed children with chronically excessive iodine intakes. Nutrients. 2016;8(7):398eng
dc.description.abstractIodine excess may impair thyroid function and trigger adverse health consequences for children. This study aims to describe iodine status among breastfed infants with high iodine exposure in the Saharawi refugee camps Algeria, and further assess thyroid function and iodine status among the children three years later. In 2010, a cross-sectional study among 111 breastfed children aged 0–6 months was performed (baseline study). In 2013, a second cross-sectional study (follow-up study) was conducted among 289 children; 213 newly selected and 76 children retrieved from baseline. Urinary iodine concentration (UIC) and breast milk iodine concentration (BMIC) were measured at baseline. UIC, thyroid hormones and serum thyroglobulin (Tg) were measured at follow-up. At baseline and follow-up, 88% and 72% had excessive iodine intakes (UIC ≥ 300 µg/L), respectively. At follow-up, 24% had a thyroid hormone disturbance and/or elevated serum Tg, including 9% with subclinical hypothyroidism (SCH), 4% with elevated fT3 and 14% with elevated Tg. Children with SCH had poorer linear growth and were more likely to be underweight than the children without SCH. Excessive iodine intakes and thyroid disturbances were common among children below four years of age in our study. Further, SCH seemed to be associated with poor growth and weight.en_US
dc.rightsAttribution CC BYeng
dc.subjectiodine excesseng
dc.subjecturinary iodine concentrationeng
dc.subjectbreast milk iodineeng
dc.subjectiodine intakeeng
dc.subjectthyroid function testseng
dc.titleThyroid function among breastfed children with chronically excessive iodine intakesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2016 The Author(s)

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