Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis. Specific Immunity in Young Children

Jenum, Synne; Sivakumaran, Dhanasekaran; Ritz, Christian; Macaden, R; Doherty, TM; Grewal, Harleen; TB Trials Study, Group
Peer reviewed, Journal article
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https://hdl.handle.net/1956/15959
Utgivelsesdato
2016
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Originalversjon
https://doi.org/10.1097/inf.0000000000001328
Sammendrag
We have explored the added value of interferon-γ (IFNγ)– inducible protein 10 as a read-out of Mycobacterium tuberculosis–specific immunity in young Indian children, where the sensitivity of the IFNγ release assays for tuberculosis is poor. Reduced frequency of indeterminate results and an increased sensitivity for tuberculosis suggest a potential for fewer missed cases with a combined IFNγ/inducible protein 10 read-out in a 4th generation IFNγ release assays.
Utgiver
Wolters Kluwer
Tidsskrift
The Pediatric Infectious Disease Journal
Opphavsrett
Copyright 2016 Wolters Kluwer Health, Inc
Attribution CC BY-NC-ND
Med mindre annet er angitt, så er denne innførselen lisensiert som Attribution CC BY-NC-ND