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dc.contributor.authorSøgaard, Anne-Johanneen_US
dc.contributor.authorRanhoff, Anette Hylenen_US
dc.contributor.authorMeyer, Haakon Een_US
dc.contributor.authorOmsland, Tone Kristinen_US
dc.contributor.authorNystad, Wencheen_US
dc.contributor.authorTell, Grethe S.en_US
dc.contributor.authorHolvik, Kristinen_US
dc.date.accessioned2019-01-28T13:10:42Z
dc.date.available2019-01-28T13:10:42Z
dc.date.issued2018-11
dc.PublishedSøgaard AJ, Ranhoff AH, Meyer HE, Omsland TK, Nystad W, Tell GST, Holvik K. The association between alcohol consumption and risk of hip fracture differs by age and gender in Cohort of Norway: a NOREPOS study. Osteoporosis International. 2018;29(11):2457–2467eng
dc.identifier.issn1433-2965
dc.identifier.issn0937-941X
dc.identifier.urihttps://hdl.handle.net/1956/19007
dc.descriptionUnder embargo until: 13.07.2019en_US
dc.description.abstractSummary: The association between alcohol consumption and hip fracture differed by gender: Men aged 30–59 years drinking frequently or 14+ gl/week had higher risk than moderate drinkers. No significant association was seen in older men. Women not drinking alcohol had higher risk than those drinking moderately both regarding frequency and amount. Introduction: We aimed to examine alcohol consumption and risk of hip fracture according to age and gender in the population-based Cohort of Norway (1994–2003). Methods: Socio-demographics, lifestyle, and health were self-reported and weight and height were measured in 70,568 men and 71,357 women ≥ 30 years. Information on subsequent hip fractures was retrieved from hospitals’ electronic patient registries during 1994–2013. Frequency of alcohol consumption was categorized: never/seldom, moderate (≤ 2–3 times/week), or frequent (≥ 4 times/week), and amount as number of glasses per week: 0, 1–6, 7–13, 14–27, and 28+. Type of alcohol (wine vs. beer/hard liquor) was also examined. Cox’s proportional hazards regression was used to estimate hazard ratios (HRs) stratified on gender and baseline age < 60 and ≥ 60 years. Results: During median 15-year follow-up, 1558 men and 2511 women suffered a hip fracture. Using moderate drinkers as reference, men < 60 years drinking frequently had multivariable adjusted HR = 1.73 (CI 1.02–2.96) for hip fracture and more than 2.5 times higher risk if they consumed 14+ glasses compared to 1–6 glasses per week. In other groups of age and gender, no statistically significant increased risk was found in those consuming the highest levels of alcohol. Compared to women with moderate or frequent alcohol use, never/seldom-drinking women had the highest fracture risk. In women, use of wine was associated with lower fracture risk than other types of alcohol. Conclusions: Risk of hip fracture was highest in men < 60 years with the highest frequency and amount of alcohol consumption and in non-drinking women.en_US
dc.language.isoengeng
dc.publisherSpringereng
dc.subjectAgeeng
dc.subjectAlcohol consumptioneng
dc.subjectAmounteng
dc.subjectFrequencyeng
dc.subjectGendereng
dc.subjectHip fractureeng
dc.titleThe association between alcohol consumption and risk of hip fracture differs by age and gender in Cohort of Norway: a NOREPOS studyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2018-08-23T10:13:13Z
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright International Osteoporosis Foundation and National Osteoporosis Foundation 2018
dc.identifier.doihttps://doi.org/10.1007/s00198-018-4627-1
dc.identifier.cristin1600200
dc.source.journalOsteoporosis International


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