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dc.contributor.authorNakken, Sigveen_US
dc.contributor.authorFournous, Ghislainen_US
dc.contributor.authorVodak, Danielen_US
dc.contributor.authorAasheim, Lars Birgeren_US
dc.contributor.authorMyklebost, Olaen_US
dc.contributor.authorHovig, Eivinden_US
dc.PublishedNakken S, Fournous G, Vodak D, Aasheim LB, Myklebost O, Hovig E. Personal Cancer Genome Reporter: Variant interpretation report for precision oncology. Bioinformatics. 2018;34(10):1778-1780eng
dc.description.abstractIndividual tumor genomes pose a major challenge for clinical interpretation due to their unique sets of acquired mutations. There is a general scarcity of tools that can (i) systematically interrogate cancer genomes in the context of diagnostic, prognostic, and therapeutic biomarkers, (ii) prioritize and highlight the most important findings and (iii) present the results in a format accessible to clinical experts. We have developed a stand-alone, open-source software package for somatic variant annotation that integrates a comprehensive set of knowledge resources related to tumor biology and therapeutic biomarkers, both at the gene and variant level. Our application generates a tiered report that will aid the interpretation of individual cancer genomes in a clinical setting.en_US
dc.publisherOxford University Presseng
dc.rightsAttribution CC BYeng
dc.titlePersonal Cancer Genome Reporter: Variant interpretation report for precision oncologyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2017 The Author(s)
dc.relation.projectNorges forskningsråd: 218241
dc.relation.projectNorges forskningsråd: 221580

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