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dc.contributor.authorZangenberg, Mikeen_US
dc.contributor.authorAbdissa, Alemsegeden_US
dc.contributor.authorJohansen, Øystein Haarklauen_US
dc.contributor.authorTesfaw, Getneten_US
dc.contributor.authorFriis, Henriken_US
dc.contributor.authorBriend, Andréen_US
dc.contributor.authorEshetu, Bezaen_US
dc.contributor.authorKurtzhals, Jørgen Anders Lindholmen_US
dc.contributor.authorGirma, Tsinuelen_US
dc.date.accessioned2020-03-20T14:54:51Z
dc.date.available2020-03-20T14:54:51Z
dc.date.issued2020
dc.PublishedZangenberg M, Abdissa A, Johansen ØH, Tesfaw G, Friis H, Briend A, Eshetu B, Kurtzhals JAL, Girma T. Critical evaluation of the appetite test for children with severe acute malnutrition. Tropical medicine & international health. 2020.eng
dc.identifier.issn1360-2276
dc.identifier.issn1365-3156
dc.identifier.urihttps://hdl.handle.net/1956/21556
dc.description.abstractOBJECTIVES: The appetite test is used to risk-stratify for children with severe acute malnutrition (SAM) in in-patient or out-patient care. The test is recommended in guidelines despite lack of evidence. We evaluated its ability to identify children at risk of a poor treatment outcome. METHODS: We conducted an observational study of children diagnosed with SAM at three health facilities in Ethiopia. The appetite test was done independently, and the result did not affect decisions about hospitalisation and clinical care. Data were analysed using mixed linear and logistic regression models. RESULTS: Appetite was tested in 298 (89%) of 334 children enrolled; 56 (19%) passed. Children failing the appetite test had a 6·6% higher weight gain per day (95% CI 2·6, 10·8) adjusted for type of treatment, oedema, duration of follow up, and age than children passing the test. We found medical complications in 179 (54%) children. Medical complications were associated with blood markers of metabolic disturbance. Children with medical complications tended to have lower weight gain than those without complications (3·5%, 95%CI -0·25, 7·0). Neither the appetite test nor medical complications were correlated with bacteraemia or treatment failure. CONCLUSIONS: Our findings question the use of the appetite test to identify children who need in-patient care. An assessment of medical complications alone could be a useful risk indicator but needs to be evaluated in other settings.en_US
dc.language.isoengeng
dc.publisherWileyeng
dc.titleCritical evaluation of the appetite test for children with severe acute malnutritionen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2020-01-24T09:36:57Z
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright 2019 John Wiley & Sons Ltd
dc.identifier.doihttps://doi.org/10.1111/tmi.13360
dc.identifier.cristin1762828
dc.source.journalTropical medicine & international health
dc.source.pagenumber424-432
dc.source.volume25
dc.source.issue4


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