Show simple item record

dc.contributor.authorJousse-Joulin, Sandrineen_US
dc.contributor.authorGatineau, Florenceen_US
dc.contributor.authorBaldini, Chiaraen_US
dc.contributor.authorBaer, Alanen_US
dc.contributor.authorBarone, Francescaen_US
dc.contributor.authorBootsma, Hendrikaen_US
dc.contributor.authorBowman, Simon Jonathanen_US
dc.contributor.authorBrito-Zerón, Pilaren_US
dc.contributor.authorCornec, Divien_US
dc.contributor.authorDörner, Thomasen_US
dc.contributor.authorde Vita, Salvatoreen_US
dc.contributor.authorFisher, Benjamin A.en_US
dc.contributor.authorHammenfors, Danielen_US
dc.contributor.authorJonsson, Malin Ven_US
dc.contributor.authorMariette, Xavieren_US
dc.contributor.authorMilić, Vera D.en_US
dc.contributor.authorNakamura, Hidekien_US
dc.contributor.authorNg, Wan-Faien_US
dc.contributor.authorNowak, Emmanuelen_US
dc.contributor.authorRamos-Casals, Manuelen_US
dc.contributor.authorRasmussen, Astriden_US
dc.contributor.authorSéror, Raphaèleen_US
dc.contributor.authorShiboski, Caroline H.en_US
dc.contributor.authorNakamura, Takashien_US
dc.contributor.authorVissink, Arjanen_US
dc.contributor.authorSaraux, Alainen_US
dc.contributor.authorDevauchelle-Pensec, Valérieen_US
dc.date.accessioned2020-04-06T13:24:49Z
dc.date.available2020-04-06T13:24:49Z
dc.date.issued2020
dc.PublishedJousse-Joulin S, Gatineau F, Baldini C, Baer A, Barone F, Bootsma H, Bowman, Brito-Zerón P, Cornec D, Dörner T, de Vita, Fisher BA, Hammenfors SD, Jonsson MV, Mariette X, Milić VD, Nakamura, Ng W, Nowak E, Ramos-Casals M, Rasmussen A, Séror, Shiboski, Nakamura T, Vissink A, Saraux A, Devauchelle-Pensec V. Weight of salivary gland ultrasonography compared to other items of the 2016 ACR/EULAR classification criteria for Primary Sjögren's syndrome. Journal of Internal Medicine. 2020;287(2):180-188eng
dc.identifier.issn0954-6820
dc.identifier.issn1365-2796
dc.identifier.urihttps://hdl.handle.net/1956/21702
dc.descriptionUnder embargo until: 2020-10-16en_US
dc.description.abstractObjective: Major salivary gland ultrasonography (SGUS) is widely used for the diagnosis of primary Sjögren’s syndrome (pSS). Our objective was to assess the contribution of SGUS compared to other items of the 2016 ACR/EULAR pSS classification criteria, based on expert opinion. Methods: A secure web‐based relational database was used by 24 experts from 14 countries to assess 512 realistic vignettes developed from data of patients with suspected pSS. Each vignette provided classification criteria items and information on history, clinical symptoms and SGUS findings. Each expert assessed 64 vignettes, and each vignette was assessed by 3 experts. A diagnosis of pSS was defined according to at least 2 of 3 experts. Validation was performed in the independent French DiapSS cohort of patients with suspected pSS. Results: A criteria‐based pSS diagnosis and SGUS findings were independently associated with an expert diagnosis of pSS (P < 0.001). The derived diagnostic weights of individual items in the 2016 ACR/EULAR criteria including SGUS were as follows: anti‐SSA, 3; focus score ≥ 1, 3; SGUS score ≥ 2, 1; positive Schirmer’s test, 1; dry mouth, 1; and salivary flow rate < 0.1 mL/min, 1. The corrected C statistic area under the curve for the new weighted score was 0.96. Adding SGUS improves the sensitivity from 90.2 % to 95.6% with a quite similar specificity 84.1% versus 82.6%. Results were similar in the DiapSS cohort: adding SGUS improves the sensitivity from 87% to 93%. Conclusion: SGUS had similar weight compared to minor items, and its addition improves the performance of the 2016 ACR/EULAR classification criteria.en_US
dc.language.isoengeng
dc.publisherWileyeng
dc.subjectUltralyd / Ultrasoundeng
dc.titleWeight of salivary gland ultrasonography compared to other items of the 2016 ACR/EULAR classification criteria for Primary Sjögren's syndromeen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2020-02-06T14:55:33Z
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright 2019 The Association for the Publication of the Journal of Internal Medicine
dc.identifier.doihttps://doi.org/10.1111/joim.12992
dc.identifier.cristin1758720
dc.source.journalJournal of Internal Medicine
dc.subject.nsiVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Reumatologi: 759
dc.subject.nsiVDP::Midical sciences: 700::Clinical medical sciences: 750::Rheumatology: 759


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record