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dc.contributor.authorZangenberg, Mikeen_US
dc.contributor.authorJohansen, Øystein Haarklauen_US
dc.contributor.authorAbdissa, Alemsegeden_US
dc.contributor.authorEshetu, Bezaen_US
dc.contributor.authorKurtzhals, Jørgen Andersen_US
dc.contributor.authorFriis, Henriken_US
dc.contributor.authorSommerfelt, Halvoren_US
dc.contributor.authorLangeland, Ninaen_US
dc.contributor.authorHanevik, Kurten_US
dc.date.accessioned2020-05-08T11:10:36Z
dc.date.available2020-05-08T11:10:36Z
dc.date.issued2019
dc.PublishedZangenberg M, Johansen ØH, Abdissa A, Eshetu, Kurtzhals JA, Friis H, Sommerfelt H, Langeland N, Hanevik K. Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia. Tropical medicine & international health. 2019;24(9):1088-1097eng
dc.identifier.issn1360-2276
dc.identifier.issn1365-3156
dc.identifier.urihttps://hdl.handle.net/1956/22140
dc.descriptionUnder embargo until: 2020-07-20en_US
dc.description.abstractObjectives: To assess the prevalence of prolonged and persistent diarrhoea, to estimate their co‐occurrence with acute malnutrition and association with demographic and clinical factors. Methods: Case–control study where cases were children under 5 years of age with diarrhoea and controls were children without diarrhoea, frequency‐matched weekly by age and district of residency. Controls for cases 0–11 months were recruited from vaccination rooms, and controls for cases 12–59 months were recruited by house visits using random locations in the catchment area of the study sites. Data were analysed by mixed model logistic regression. Results: We enrolled 1134 cases and 946 controls. Among the cases, 967 (85%) had acute diarrhoea (AD), 129 (11%) had ProD and 36 (3.2%) had PD. More cases had acute malnutrition at enrolment (17% vs. 4%, P < 0.0001) and more were born prematurely (5.7% vs. 1.8%, P < 0.0001) than controls. About 75% of ProPD cases did not have acute malnutrition. Cases with AD and ProPD had different symptomatology, even beyond illness duration. Conclusions: ProPD is common among children presenting with diarrhoea and is not confined to children with acute malnutrition. There is an urgent need for studies assessing causes of ProPD with and without acute malnutrition to develop treatment guidelines for these conditions.en_US
dc.language.isoengeng
dc.publisherWileyeng
dc.titleProlonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopiaen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2020-01-14T13:04:22Z
dc.description.versionacceptedVersionen_US
dc.rights.holderCopyright 2019 John Wiley & Sons Ltd
dc.identifier.doihttps://doi.org/10.1111/tmi.13291
dc.identifier.cristin1712389
dc.source.journalTropical medicine & international health
dc.relation.projectNorges forskningsråd: 255571


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