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dc.contributor.authorMartinsen, Einar Marius Hjellestaden_US
dc.contributor.authorEagan, Tomas Mikalen_US
dc.contributor.authorLeiten, Elise Orvedalen_US
dc.contributor.authorNordeide, Elien_US
dc.contributor.authorBakke, Per S.en_US
dc.contributor.authorLehmann, Sverreen_US
dc.contributor.authorNielsen, Runeen_US
dc.date.accessioned2020-05-14T11:55:18Z
dc.date.available2020-05-14T11:55:18Z
dc.date.issued2019-05-02
dc.PublishedMartinsen EMH, Eagan TML, Leiten EO, Nordeide E, Bakke PS, Lehmann S, Nielsen R. Motivation and response rates in bronchoscopy studies. Multidisciplinary Respiratory Medicine. 2019;14:14eng
dc.identifier.issn2049-6958
dc.identifier.issn1828-695X
dc.identifier.urihttps://hdl.handle.net/1956/22266
dc.description.abstractBackground Bronchoscopy is frequently used to sample the lower airways in lung microbiome studies. Despite being a safe procedure, it is associated with discomfort that may result in reservations regarding participation in research bronchoscopy studies. Information on participation in research bronchoscopy studies is limited. We report response rates, reasons for non-response, motivation for participation, and predictors of participation in a large-scale single-centre bronchoscopy study (“MicroCOPD”). Methods Two hundred forty-nine participants underwent at least one bronchoscopy in addition to being examined by a physician, having lung function tested, and being offered a CT scan of the heart and lungs (subjects > 40 years). Each participant was asked an open question regarding motivation. Non-response reasons were gathered, and response rates were calculated. Results The study had a response rate just above 50%, and men had a significantly higher response rate than women (56.5% vs. 44.8%, p = 0.01). Procedural fear was the most common non-response reason. Most participants participated due to perceived personal benefit, but a large proportion did also participate to help others and contribute to science. Men were less likely to give exclusive altruistic motives, whereas subjects with asthma were more likely to report exclusive personal benefit as main motive. Conclusion Response rates of about 50% in bronchoscopy studies make large bronchoscopy studies feasible, but the fact that participants are motivated by their own health status places a large responsibility on the investigators regarding the accuracy of the provided study information.en_US
dc.language.isoengeng
dc.publisherSpringereng
dc.rightsAttribution CC BYeng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/eng
dc.titleMotivation and response rates in bronchoscopy studiesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2019-12-09T13:28:18Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 The authors
dc.identifier.doihttps://doi.org/10.1186/s40248-019-0178-3
dc.identifier.cristin1709938
dc.source.journalMultidisciplinary Respiratory Medicine


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