dc.contributor.author | Nilsen, Kathrin Skorpa | en_US |
dc.contributor.author | Lund-Johansen, Morten | en_US |
dc.contributor.author | Nordahl, Stein Helge | en_US |
dc.contributor.author | Finnkirk, Monica Katrine | en_US |
dc.contributor.author | Goplen, Frederik Kragerud | en_US |
dc.date.accessioned | 2020-05-28T12:15:30Z | |
dc.date.available | 2020-05-28T12:15:30Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0194-5998 | |
dc.identifier.issn | 1097-6817 | |
dc.identifier.uri | https://hdl.handle.net/1956/22398 | |
dc.description.abstract | Objectives: To study the development of dizziness, caloric function, and postural sway during long-term observation of untreated vestibular schwannoma patients.
Study Design: Retrospective review of a prospectively maintained longitudinal cohort.
Setting: Tertiary referral hospital.
Subjects and Methods: Patients with vestibular schwannoma undergoing wait-and-scan management were included—specifically, those who did not require treatment during a minimum radiologic follow-up of 1 year. Baseline data and follow-up included magnetic resonance imaging, posturography, bithermal caloric tests, and a dizziness questionnaire. Main outcomes were prevalence of moderate to severe dizziness, canal paresis, and postural instability at baseline and follow-up, as compared with McNemar’s test.
Results: Out of 433 consecutive patients with vestibular schwannoma, 114 did not require treatment during follow-up and were included. Median radiologic follow-up was 10.2 years (interquartile range, 4.5 years). Age ranged from 31 to 78 years (mean, 59 years; SD, 10 years; 62% women). Median tumor volume at baseline was 139 mm3 (interquartile range, 314 mm3). This did not change during follow-up (P = .446). Moderate to severe dizziness was present in 27% at baseline and 19% at follow-up (P = .077). Postural unsteadiness was present in 17% at baseline and 21% at follow-up (P = .424). Canal paresis was present in 51% at baseline and 56% at follow-up (P = .664).
Conclusions: There was no significant change in the prevalence of dizziness, postural sway, or canal paresis during conservative management of vestibular schwannoma, while tumor volume remained unchanged. This indicates a favorable prognosis in these patients with regard to vestibular symptoms. | en_US |
dc.language.iso | eng | eng |
dc.publisher | Sage | eng |
dc.title | Long-term effects of conservative management of vestibular schwannoma on dizziness, balance, and caloric function | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2020-02-03T08:33:12Z | |
dc.description.version | acceptedVersion | en_US |
dc.rights.holder | Copyright American Academy of Otolaryngology–Head and Neck Surgery Foundation 2019 | |
dc.identifier.doi | https://doi.org/10.1177/0194599819860831 | |
dc.identifier.cristin | 1760275 | |
dc.source.journal | Otolaryngology - Head and Neck Surgery | |
dc.source.pagenumber | 846-851 | |
dc.identifier.citation | Otolaryngology - Head and Neck Surgery. 2019, 161 (5), 846-851. | |
dc.source.volume | 161 | |
dc.source.issue | 5 | |