dc.contributor.author | Burger, Bram | |
dc.contributor.author | Lereim, Ragnhild Reehorst | |
dc.contributor.author | Berven, Frode | |
dc.contributor.author | Barsnes, Harald | |
dc.date.accessioned | 2020-06-25T09:47:01Z | |
dc.date.available | 2020-06-25T09:47:01Z | |
dc.date.issued | 2019 | |
dc.Published | Burger B, Lereim RR, Berven F, Barsnes H. Detecting single amino acids and small peptides by combining isobaric tags and peptidomics. European Journal of Mass Spectrometry. 2019;.25(6):451–456 | eng |
dc.identifier.issn | 1469-0667 | en_US |
dc.identifier.issn | 1751-6838 | en_US |
dc.identifier.uri | https://hdl.handle.net/1956/22962 | |
dc.description.abstract | Single amino acids and small endogenous peptides play important roles in maintaining a properly functioning organism. These molecules are however currently only routinely identified in targeted approaches. In a small proof-of-concept mass spectrometry experiment, we found that by combining isobaric tags and peptidomics, and by targeting singly charged molecules, we were able to identify a significant amount of single amino acids and small endogenous peptides using a basic mass-based identification approach. While there is still room for improvement, our simple test indicates that a limited amount of extra work when setting up the mass spectrometry experiment could potentially lead to a wealth of additional information. | en_US |
dc.language.iso | eng | eng |
dc.publisher | SAGE | en_US |
dc.title | Detecting single amino acids and small peptides by combining isobaric tags and peptidomics | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2019-11-11T14:59:11Z | |
dc.description.version | acceptedVersion | en_US |
dc.rights.holder | Copyright 2019 The Authors | en_US |
dc.identifier.doi | https://doi.org/10.1177/1469066719857006 | |
dc.identifier.cristin | 1723769 | |
dc.source.journal | European Journal of Mass Spectrometry | |
dc.relation.project | Bergens forskningsstiftelse: BFS2016REK02 | |
dc.relation.project | Norges forskningsråd: 251235 | |
dc.identifier.citation | European Journal of Mass Spectrometry. 2019, 25 (6), 451–456. | |