Vis enkel innførsel

dc.contributor.authorSteigen, Sonja Een_US
dc.contributor.authorSøland, Tine Mereteen_US
dc.contributor.authorNginamau, Elisabeth Sivyen_US
dc.contributor.authorLaurvik, Heleneen_US
dc.contributor.authorCostea, Daniela-Elenaen_US
dc.contributor.authorJohannessen, Anne Christineen_US
dc.contributor.authorJebsen, Peter Wilhelmen_US
dc.contributor.authorBjerkli, Inger-Heidien_US
dc.contributor.authorUhlin-Hansen, Larsen_US
dc.contributor.authorHadler-Olsen, Elin Synnøveen_US
dc.date.accessioned2020-07-02T09:11:00Z
dc.date.available2020-07-02T09:11:00Z
dc.date.issued2020
dc.PublishedSteigen, Søland TM, Nginamau, Laurvik H, Costea, Johannessen AC, Jebsen PW, Bjerkli I, Uhlin-Hansen L, Hadler-Olsen ES. Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?. Journal of Oral Pathology & Medicine. 2020eng
dc.identifier.issn0904-2512
dc.identifier.issn1600-0714
dc.identifier.urihttps://hdl.handle.net/1956/23235
dc.description.abstractBackground: Numerous studies have been presented on histological grading of oral squamous cell carcinomas (OSCC) for predicting survival, but uncertainty of their usefulness rises due to discordances of results. A scoring system should be robust and well validated, and intra‐ and interrater agreement can be used as a tool to visualize the strength of reproducibility. Methods: Here, we present an intra‐ and inter‐observer study on evaluation of OSCC using some of the most common histopathological parameters. The observers were from different Norwegian university hospitals, and calibration to ensure accuracy was first performed. Percentage of the agreement was calculated for the score made by the individual observer at different times, as well as between pairs of observers. Results: The evaluation made by the same observer at two different time points (intrarater) correlated better than observations made by different participants (interrater). In an attempt to increase the rate of agreement, many of the parameters were either dichotomized into simply low‐ and high grade, or to a three‐tier system when more than three options in the original design. This increased the concurrence with 15.4% for the intrarater and with 23% for the interrater comparisons. Conclusion: High agreement for histopathological parameters can be difficult to obtain on hematoxylin and eosin staining in scoring systems with many options. A simpler system might be more advantageous to achieve higher degree of reproducibility.en_US
dc.language.isoengeng
dc.publisherWileyeng
dc.rightsAttribution CC BYeng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0eng
dc.titleGrading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?en_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2020-02-05T11:31:08Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 The Author(s)
dc.identifier.doihttps://doi.org/10.1111/jop.12990
dc.identifier.cristin1785030
dc.source.journalJournal of Oral Pathology & Medicine


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Attribution CC BY
Med mindre annet er angitt, så er denne innførselen lisensiert som Attribution CC BY