dc.contributor.author | Borda, Miguel Germán | en_US |
dc.contributor.author | Sønnesyn, Hogne | en_US |
dc.contributor.author | Steves, Claire J. | en_US |
dc.contributor.author | Vik-Mo, Audun Osland | en_US |
dc.contributor.author | Perez-Zepeda, Mario Ulises | en_US |
dc.contributor.author | Årsland, Dag | en_US |
dc.date.accessioned | 2020-08-06T13:28:52Z | |
dc.date.available | 2020-08-06T13:28:52Z | |
dc.date.issued | 2019 | |
dc.Published | Borda, Sønnesyn, Steves, Vik-Mo, Perez-Zepeda, Årsland. Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease. Dementia and geriatric cognitive disorders extra. 2019;9:176–183 | eng |
dc.identifier.issn | 1664-5464 | |
dc.identifier.uri | https://hdl.handle.net/1956/23533 | |
dc.description.abstract | Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary analysis of the Dementia Study of Western Norway (Demvest). For this study, we analysed a sample of 186 patients, 116 with AD and 70 with DLB. Subjects were included at a time in which mild dementia was diagnosed according to consensus criteria after comprehensive standardized assessment. Frailty was evaluated retrospectively using a frailty index generated from existing data. The cut-off value used to classify an older adult as frail was 0.25. Results: The prevalence of frailty was 25.81% (n = 48). In the DLB group, 37.14% (n = 26) were classified as frail, compared to 18.97% (n = 22) of those with AD (p < 0.001). The adjusted multivariate analysis revealed an OR of 2.45 (1.15–5.23) for being frail in those with DLB when using AD as the reference group. Conclusion: Frailty was higher than expected in both types of dementia. The prevalence of frailty was higher in those with DLB compared to AD. This new finding underscores the need for a multi-systems approach in both dementias, with a particular focus on DLB. | en_US |
dc.language.iso | eng | eng |
dc.publisher | Karger | eng |
dc.rights | Attribution-Non Commercial-No Derivatives CC BY-NC-ND | eng |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | eng |
dc.title | Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.date.updated | 2019-11-12T09:45:53Z | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2019 The Authors | |
dc.identifier.doi | https://doi.org/10.1159/000496537 | |
dc.identifier.cristin | 1709816 | |
dc.source.journal | Dementia and geriatric cognitive disorders extra | |