Show simple item record

dc.contributor.authorDillekås, Hannaen_US
dc.contributor.authorRogers, Michael S.en_US
dc.contributor.authorStraume, Oddbjørnen_US
dc.PublishedDillekås HE, Rogers MS, Straume O. Are 90% of deaths from cancer caused by metastases?. Cancer Medicine. 2019;8(12):5574-5576eng
dc.description.abstractNumerous publications have stated that metastases are responsible for 90% of cancer deaths, but data underlying this assertion has been lacking. Our objective was to determine what proportions of cancer deaths are caused by metastases. Population‐based data from the Cancer Registry of Norway for the years 2005‐2015 was analyzed. We compared all deaths in the Norwegian population where a cancer diagnosis was registered as cause of death. Deaths caused by cancer, with and without metastases, were analyzed, by sex and tumor group. For solid tumors, 66.7% of cancer deaths were registered with metastases as a contributing cause. Proportions varied substantially between tumor groups. Our data support the idea that the majority of deaths from solid tumors are caused by metastases. Thus, a better understanding of the biology of metastases and identification of druggable targets involved in growth at the metastatic site is a promising strategy to reduce cancer mortality.en_US
dc.rightsAttribution CC BYeng
dc.titleAre 90% of deaths from cancer caused by metastases?en_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2019 The Authors
dc.source.journalCancer Medicine

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution CC BY
Except where otherwise noted, this item's license is described as Attribution CC BY