dc.contributor.author | Svendal, Gjertrud | en_US |
dc.contributor.author | Fasmer, Ole Bernt | en_US |
dc.contributor.author | Engeland, Anders | en_US |
dc.contributor.author | Berk, Michael | en_US |
dc.contributor.author | Lund, Anders | en_US |
dc.date.accessioned | 2013-05-14T11:12:24Z | |
dc.date.available | 2013-05-14T11:12:24Z | |
dc.date.issued | 2012-11-27 | eng |
dc.Published | BMC Medicine 2012, 10:148 | eng |
dc.identifier.issn | 1741-7015 | |
dc.identifier.uri | https://hdl.handle.net/1956/6606 | |
dc.description.abstract | Background: Studies have shown a correlation between bipolar disorder and diabetes mellitus. It is unclear if this correlation is a part of common pathophysiological pathways, or if medication for bipolar disorder has negative effects on blood sugar regulation. Methods: The Norwegian prescription database was analyzed. Prescriptions for lithium, lamotrigine, carbamazepine and valproate were used as proxies for bipolar disorder. Prescriptions for insulin and oral anti-diabetic agents were used as proxies for diabetes mellitus. We explored the association between medication for bipolar disorder and diabetes medication by logistic regression. Results: We found a strong association between concomitant use of medication to treat diabetes mellitus and mood stabilizers for the treatment of bipolar disorder. Females had a 30% higher risk compared to men of being treated for both disorders. Persons using oral anti-diabetic agents had higher odds of receiving valproate than either lithium or lamotrigine. Use of insulin as monotherapy seemed to have lower odds than oral anti-diabetic agents of co-prescription of mood stabilizers, compared to the general population. Conclusions: This study showed a strong association between the use of mood stabilizers and anti-diabetic agents. The association was stronger among women than men. | en_US |
dc.language.iso | eng | eng |
dc.publisher | BioMed Central | eng |
dc.rights | Attribution CC BY | eng |
dc.rights.uri | http://creativecommons.org/licenses/by/2.0/ | eng |
dc.title | Co-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differences | en_US |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2012 Svendal et al; licensee BioMed Central Ltd. | |
dc.identifier.doi | https://doi.org/10.1186/1741-7015-10-148 | |
dc.identifier.cristin | 968190 | |
dc.source.journal | BMC Medicine | |
dc.source.40 | 10 | |
dc.source.14 | 148 | |