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dc.contributor.authorSvendal, Gjertruden_US
dc.contributor.authorFasmer, Ole Bernten_US
dc.contributor.authorEngeland, Andersen_US
dc.contributor.authorBerk, Michaelen_US
dc.contributor.authorLund, Andersen_US
dc.date.accessioned2013-05-14T11:12:24Z
dc.date.available2013-05-14T11:12:24Z
dc.date.issued2012-11-27eng
dc.PublishedBMC Medicine 2012, 10:148eng
dc.identifier.issn1741-7015
dc.identifier.urihttps://hdl.handle.net/1956/6606
dc.description.abstractBackground: Studies have shown a correlation between bipolar disorder and diabetes mellitus. It is unclear if this correlation is a part of common pathophysiological pathways, or if medication for bipolar disorder has negative effects on blood sugar regulation. Methods: The Norwegian prescription database was analyzed. Prescriptions for lithium, lamotrigine, carbamazepine and valproate were used as proxies for bipolar disorder. Prescriptions for insulin and oral anti-diabetic agents were used as proxies for diabetes mellitus. We explored the association between medication for bipolar disorder and diabetes medication by logistic regression. Results: We found a strong association between concomitant use of medication to treat diabetes mellitus and mood stabilizers for the treatment of bipolar disorder. Females had a 30% higher risk compared to men of being treated for both disorders. Persons using oral anti-diabetic agents had higher odds of receiving valproate than either lithium or lamotrigine. Use of insulin as monotherapy seemed to have lower odds than oral anti-diabetic agents of co-prescription of mood stabilizers, compared to the general population. Conclusions: This study showed a strong association between the use of mood stabilizers and anti-diabetic agents. The association was stronger among women than men.en_US
dc.language.isoengeng
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/eng
dc.titleCo-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differencesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2012 Svendal et al; licensee BioMed Central Ltd.
dc.identifier.doihttps://doi.org/10.1186/1741-7015-10-148
dc.identifier.cristin968190
dc.source.journalBMC Medicine
dc.source.4010
dc.source.14148


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