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dc.contributor.authorGregersen, Kineen_US
dc.contributor.authorLind, Ragna Anneen_US
dc.contributor.authorValeur, Jørgenen_US
dc.contributor.authorBjørkkjær, Tormoden_US
dc.contributor.authorBerstad, Arnolden_US
dc.contributor.authorLied, Gülen Arslanen_US
dc.PublishedInternational Journal of General Medicine 3: 383-392eng
dc.description.abstractShort-term duodenal administration of n-3 polyunsaturated fatty acid (PUFA)-rich seal oil may improve gastrointestinal complaints in patients with subjective food hypersensitivity, as well as joint pain in patients with inflammatory bowel disease (IBD). The aim of the present explorative pilot study was to investigate whether 10-day open treatment with seal oil, 10 mL self-administrated via a nasoduodenal tube 3 times daily, could also benefit nongastrointestinal complaints and quality of life (QoL) in patients with subjective food hypersensitivity. Twenty-six patients with subjective food hypersensitivity, of whom 25 had irritable bowel syndrome (IBS), were included in the present study. Before and after treatment and 1 month posttreatment, patients filled in the Ulcer Esophagitis Subjective Symptoms Scale (UESS) and the Gastrointestinal Symptom Rating Scale (GSRS) for gastrointestinal symptoms and subjective health complaints (SHC) inventory for nongastrointestinal symptoms in addition to short form of the Nepean dyspepsia index (SF-NDI) for evaluation of QoL. Compared with baseline, gastrointestinal, as well as nongastrointestinal, complaints and QoL improved significantly, both at end of treatment and 1 month posttreatment. The consistent improvements following seal oil administration warrant further placebo-controlled trials for confirmation of effect.en_US
dc.publisherDove Medical Presseng
dc.relation.ispartof<a href="" target="blank">Subjective food hypersensitivity</a>eng
dc.rightsAttribution CC BYeng
dc.titleDuodenal administered seal oil for patients with subjective food hypersensitivity: an explorative open pilot studyen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2010 Gregersen et al, publisher and licensee Dove Medical Press Ltd.
dc.source.journalInternational Journal of General Medicine

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