Blar i Department of Clinical Science på utgivelsesdato
Viser treff 101-120 av 2343
-
A study on the effects of serotonin reuptake inhibitors on platelet function in whole blood and platelet concentrates
(Master thesis, 2010-05-19)Background: Several studies report that patients who use serotonin reuptake inhibitors (SRIs) to treat depression may have increased risk of bleeding, particularly from the gastrointestinal tract. This may be related to ... -
Herbal plants used in traditional Chinese medicine as a source of compounds with potential medical utilities - identification, characterization and organization
(Master thesis, 2010-05-19)The history and knowledge of Chinese herbal medicine is over 3000 years old, and over 10 000 herbs are recorded and are in use for different conditions. This is an enormous amount of knowledge that can be used to find new ... -
Determination of conformations adopted by CXCR4 and CCR5 at the cell surface
(Master thesis, 2010-05-20)The chemokines and their receptors constitute many important physiological functions in the human body. The chemokine receptors belong to the family of G-protein coupled receptors, characterized by 7 α-helices penetrating ... -
Legemidler og porfyri: Utvikling av et system for innhenting av farmakologisk informasjon fra legemiddelprodusenter
(Master thesis, 2010-05-20)Akutte porfyrisykdommer er arvelig betingede metabolske sykdommer som forekommer sjeldent. Bruk av vanlige legemidler kan utløse alvorlige, akutte anfall hos pasienter med genetisk disposisjon for akutt porfyri. Nasjonalt ... -
Giardiasis : with emphasis on treatment and post-infectious manifestations
(Doctoral thesis, 2010-05-21) -
Switch from stress response to homeobox transcription factors in Adipose tissue after profound fat loss
(Peer reviewed; Journal article, 2010-06-09)Background In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance ... -
Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults
(Peer reviewed; Journal article, 2010-06-10)Background Arachnoid cyst (AC) fluid has not previously been compared with cerebrospinal fluid (CSF) from the same patient. ACs are commonly referred to as containing "CSF-like fluid". The objective of this study was to ... -
Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer
(Peer reviewed; Journal article, 2010-06-21)Background The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and ... -
Forekomst og håndtering av legemiddelinteraksjoner med warfarin ved Sykehuset Buskerud
(Master thesis, 2010-06-21)Denne studien kartlegger forekomsten av legemiddelinteraksjoner med warfarin hos 105 pasienter skrevet ut fra seks sengeposter ved medisinsk klinikk, kirurgisk klinikk og nevromuskulær klinikk ved Sykehuset Buskerud. ... -
Intestinal fermentation in patients with self-reported food hypersensitivity: painful, but protective?
(Peer reviewed; Journal article, 2010-07-03)Purpose: Enterometabolic disturbances may cause meal-related symptoms. We performed a functional evaluation of the intestinal microflora in patients with unexplained, self-reported food hypersensitivity by measuring fecal ... -
Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells
(Peer reviewed; Journal article, 2010-07-09)Background Several observations suggest that immunological events early after chemotherapy, possibly during the period of severe treatment-induced cytopenia, are important for antileukemic immune reactivity in acute myeloid ... -
Homocysteine-lowering clinical trials in Norway. Cardiovascular and cancer outcomes in the Western Norway B Vitamin Intervention Trial and the Norwegian Vitamin Trial
(Doctoral thesis, 2010-09-17)Introduction: Observational studies have reported associations between levels of the amino acid homocysteine in the circulation and risk of cardiovascular disease. Oral administration of the synthetic B vitamins folic acid ... -
Patient safety in surgical environments: Cross-countries comparison of psychometric properties and results of the Norwegian version of the Hospital Survey on Patient Safety
(Peer reviewed; Journal article, 2010-09-22)Background: How hospital health care personnel perceive safety climate has been assessed in several countries by using the Hospital Survey on Patient Safety (HSOPS). Few studies have examined safety climate factors in ... -
Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey
(Peer reviewed; Journal article, 2010-09-27)Background Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with HRQoL ... -
Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation
(Doctoral thesis, 2010-10-08)Background: Self-reported food hypersensitivity remains unexplained in most cases. Abdominal symptoms, typically consistent with the irritable bowel syndrome (IBS), are common in patients with such unexplained, self-reported ... -
High-intensity Interval Training after Percutaneous Coronary Intervention. A randomized controlled study evaluating the effect of exercise training on late luminal loss with relationship to inflammation and endothelial function
(Doctoral thesis, 2010-10-22)Introduction: In spite of consistent scientific documentation of the beneficial effects of exercise training programs in coronary artery disease (CAD), exercise training is a remarkably underutilized (1) and probably also ... -
Genetic biomarkers as prognostic and predictive factors in metastatic malignant melanoma
(Doctoral thesis, 2010-10-26)Malignant melanoma is one of the most chemoresistant malignancies in man. Although effort is put into developing new drugs to treat metastatic melanoma, still dacarbazine, an alkylating agent approved in 1975 for therapeutic ... -
emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway
(Peer reviewed; Journal article, 2010-11-20)In order to investigate molecular characteristics of beta-hemolytic streptococcal isolates from western Norway, we analysed the entire emm gene sequences, obtained superantigen gene profiles and determined the prevalence ... -
High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer
(Peer reviewed; Journal article, 2011)Background: Endometrial cancer incidence is increasing in industrialised countries. High body mass index (BMI, kg m−2) is associated with higher risk for disease. We wanted to investigate if BMI is related to clinico-pathological ... -
Risk of Misclassification of decompression sickness
(Peer reviewed; Journal article, 2011)Decompression sickness (DCS) is classified on the basis of which organ system is affected, and neurological DCS is considered more severe than DCS in joints and skin with respect to response to recompression treatment and ...