Zhang, Juan; Terán, Graciela; Popa, Mihaela-Lucia; Madapura, Harsha; Ladds, Marcus J.G.W.; Lianoudaki, Danai; Grünler, Jacob; Arsenian-Henriksson, Marie; McCormack, Emmet; Rottenberg, Martin Enrique; Catrina, Sergiu-Bogdan; Laín, Sonia; Darekar, Suhas (Journal article; Peer reviewed, 2021)
Dihydroorotate dehydrogenase (DHODH) is essential for the de novo synthesis of pyrimidine ribonucleotides, and as such, its inhibitors have been long used to treat autoimmune diseases and are in clinical trials for cancer ...