• Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections 

      Jahagirdar, Sanjeevan; Morris, Lorna; Benis, Nirupama; Oppegaard, Oddvar; Svenson, Mattias; Hyldegaard, Ole; Skrede, Steinar; Norrby-Teglund, Anna; Bruun, Trond; Rath, Eivind; Nedrebø, Torbjørn; Arnell, Per; Rosen, Anders; Hedetoft, Morten; Madsen, Martin B.; Svensson, Mattias; Snäll, Johanna; Karlsson, Ylva; Nekludov, Michael; Martins dos Santos, Vitor A. P.; Saccenti, Edoardo (Journal article; Peer reviewed, 2022)
      Background: Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial ...
    • Clinical Characteristics and Histopathology in Suspected Necrotizing Soft Tissue Infections 

      Gundersen, Ingunn Margareetta; Berget, Ellen; Haugland, Hans Kristian; Bruun, Trond; Almeland, Stian Kreken; Assmus, Jörg; Rath, Eivind; Norrby-Teglund, Anna; Skrede, Steinar; Mosevoll, Knut Anders (Journal article; Peer reviewed, 2022)
      Background Necrotizing soft tissue infections (NSTIs) are severe diseases with high morbidity and mortality. The diagnosis is challenging. Several guidelines recommend tissue biopsies as an adjunct diagnostic in routine ...
    • Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study 

      Rath, Eivind; Palma Medina, Laura M.; Jahagirdar, Sanjeevan; Mosevoll, Knut Anders; Damås, Jan Kristian; Madsen, Martin B.; Svensson, Mattias; Hyldegaard, Ole; Martins dos Santos, Vitor A.P.; Saccenti, Edoardo; Norrby-Teglund, Anna; Skrede, Steinar; Bruun, Trond (Journal article; Peer reviewed, 2023)
      Objective Early stages with streptococcal necrotizing soft tissue infections (NSTIs) are often difficult to discern from cellulitis. Increased insight into inflammatory responses in streptococcal disease may guide correct ...