Blar i Department of Clinical Science på forfatter "Tangney, Mark"
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Development of a bioluminescent nitroreductase probe for preclinical imaging
Vorobyeva, Anzhelika G.; Stanton, Michael; Godinat, Aurélien; Lund, Kjetil B.; Karateev, Grigory G.; Francis, Kevin P.; Allen, Elizabeth; Gelovani, Juri G.; McCormack, Emmet; Tangney, Mark; Dubikovskaya, Elena A. (Peer reviewed; Journal article, 2015-06-25)Bacterial nitroreductases (NTRs) have been widely utilized in the development of novel antibiotics, degradation of pollutants, and gene-directed enzyme prodrug therapy (GDEPT) of cancer that reached clinical trials. In ...