Department of Clinical Science: Nye registreringer
Viser treff 21-40 av 2217
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Exploring the Patient Perspective of Bone Sarcoma Survivors Who Have Undergone Particle Radiotherapy Abroad
(Journal article; Peer reviewed, 2023)Background/Aim: Sarcoma patients’ experiences of their health-related quality of life and late effects following particle therapy are sparse. Such knowledge is essential to optimize treatment compliance and follow-up care ... -
Validation of a modified South African triage scale in a high-resource setting: a retrospective cohort study
(Journal article; Peer reviewed, 2023-03-20)Background: Triage systems are widely used in emergency departments, but are not always validated. The South African Triage Scale (SATS) has mainly been studied in resource-limited settings. The aim of this study was to ... -
An external quality assessment feasibility study; cross laboratory comparison of haemagglutination inhibition assay and microneutralization assay performance for seasonal influenza serology testing: A FLUCOP study
(Journal article; Peer reviewed, 2023)Introduction: External Quality Assessment (EQA) schemes are designed to provide a snapshot of laboratory proficiency, identifying issues and providing feedback to improve laboratory performance and inter-laboratory agreement ... -
Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study
(Journal article; Peer reviewed, 2023)Purpose Dietary intake may have pronounced effects on circulating biomarker concentrations. Therefore, the aim was to provide a descriptive overview of serum metabolite concentrations in relation to time since last meal, ... -
Self-management and hospitalization in 615 Swedish patients with Addison's disease during the coronavirus disease 2019 pandemic: a retrospective study
(Journal article; Peer reviewed, 2023)Objective Autoimmune Addison's disease (AAD) entails a chronic adrenal insufficiency and is associated with an increased risk of severe infections. It is, however, unknown how patients with AAD were affected by the ... -
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
(Journal article; Peer reviewed, 2023)Schizophrenia (SCZ) and bipolar disorder (BD) share clinical characteristics, genetic susceptibility, and immune alterations. We aimed to identify differential transcriptional patterns in peripheral blood cells of patients ... -
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
(Journal article; Peer reviewed, 2023)Autism spectrum disorder (ASD) is a highly heritable condition with a large variation in cognitive function. Here we investigated the shared genetic architecture between cognitive traits (intelligence (INT) and educational ... -
Pregestational maternal risk factors for preterm and term preeclampsia: A population-based cohort study
(Journal article; Peer reviewed, 2023)Introduction Most studies on factors affecting the risk of preeclampsia have not separated preterm from term preeclampsia, and we still know little about whether the predisposing conditions have a differentiated effect ... -
Virtual reality simulation training in stroke thrombectomy centers with limited patient volume—Simulator performance and patient outcome
(Journal article; Peer reviewed, 2023)Background Virtual reality simulation training may improve the technical skills of interventional radiologists when establishing endovascular thrombectomy at limited-volume stroke centers. The aim of this study was to ... -
Cardiac Function and Early Risk Markers for Cardiovascular Disease in Children and Young Adults Surviving Severe Childhood Disease
(Doctoral thesis, 2023-11-03)Sammendrag på norsk Bakgrunn Prosessene som ligger bak utvikling av hjerte-kar sykdom starter tidlig i livet og er avhengig av antall risikofaktorer og debuttidspunkt av disse. Noen grupper er mer utsatt for hjerte-kar ... -
Highly contiguous genomes of human clinical isolates of Giardia duodenalis reveal assemblage-and sub-assemblage-specific presence–absence variation in protein-coding genes
(Journal article; Peer reviewed, 2023)Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a widespread gastrointestinal protozoan parasite with debated taxonomic status. Currently, eight distinct genetic sub-groups, termed assemblages A–H, are defined ... -
Revisiting the prognostic role of FLT3 mutations in acute myelogenous leukemia
(Journal article; Peer reviewed, 2023)Introduction: Approximately one-third of patients with acute myelogenous leukemia (AML) harbor mutations in the fms-like tyrosine kinase 3 (FLT3) gene. The features regarding prognostic impact of FLT3 mutated AML have been ... -
Pretransplant systemic metabolic profiles in allogeneic hematopoietic stem cell transplant recipients - identification of patient subsets with increased transplant-related mortality
(Journal article; Peer reviewed, 2023)Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is used in the treatment of high-risk acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS); however, the treatment has high risk of severe ... -
Systemic interferon type I and B cell responses are impaired in autoimmune polyendocrine syndrome type 1
(Journal article; Peer reviewed, 2023)Autoimmune polyendocrine syndrome type I (APS-1) is caused by mutations in the autoimmune regulator (AIRE) gene and characterised clinically by multiple autoimmune manifestations and serologically by autoantibodies against ... -
Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease
(Journal article; Peer reviewed, 2023)Background: Identification of aggressive low-stage endometrial cancers is challenging. So far, studies have failed to pinpoint robust features or biomarkers associated with risk of recurrence for these patients. Methods: ... -
The role of inflammation in anxiety and depression in the European U-BIOPRED asthma cohorts
(Journal article; Peer reviewed, 2023)Background: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate the ... -
In vitro quality of cold and delayed cold-stored platelet concentrates from interim platelet units during storage for 21 days
(Journal article; Peer reviewed, 2023)Background and Objectives: Based on previous success using apheresis platelets, we wanted to investigate the in vitro quality and platelet function in continuously cold-stored and delayed cold-stored platelet concentrates ... -
Identification of Cumin (Cuminum cyminum) MicroRNAs through Deep Sequencing and Their Impact on Plant Secondary Metabolism
(Journal article; Peer reviewed, 2023-04-25)The pharmacological properties of plants lie in the content of secondary metabolites that are classified into different categories based on their biosynthesis, structures, and functions. MicroRNAs (miRNAs) are small ... -
Clues to Diagnosis and Clinical Outcomes in Autoimmune Addison’s Disease
(Doctoral thesis, 2023-10-23)Forsinka diagnose av autoimmun Addisons sjukdom (AAS) aukar risikoen for ei potensielt dødeleg binyrekrise. Ved etablert sjukdom er det stor variasjon i kliniske utfall, med forskjellar i risiko for binyrekriser, kardiovaskulær ... -
Disturbed lipid profile in common variable immunodeficiency – a pathogenic loop of inflammation and metabolic disturbances
(Journal article; Peer reviewed, 2023)The relationship between metabolic and inflammatory pathways play a pathogenic role in various cardiometabolic disorders and is potentially also involved in the pathogenesis of other disorders such as cancer, autoimmunity ...