• Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells 

      Steiner, Ivana; Flores-Tellez, Teresita del N.J.; Mevel, Renaud; Ali, Amin; Wang, Pengbo; Schofield, Pieta; Behan, Caron; Forsythe, Nicholas; Ashton, Garry; Taylor, Catherine; Mills, Ian Geoffrey; Oliveira, Pedro; McDade, Simon S.; Zaiss, Dietmar M.; Choudhury, Ananya; Lacaud, Georges; Baena, Esther (Journal article; Peer reviewed, 2023)
      The emergence of castration-resistant prostate cancer remains an area of unmet clinical need. We recently identified a subpopulation of normal prostate progenitor cells, characterized by an intrinsic resistance to androgen ...