Wang, Shan; Rhijn, Jon-Ruben van; Akkouh, Ibrahim Ahmed; Kogo, Naoki; Maas, Nadine; Bleeck, Anna; Ortiz, Irene Santisteban; Lewerissa, Elly; Wu, Ka Man; Schoenmaker, Chantal; Djurovic, Srdjan; van Bokhoven, Hans; Kleefstra, Tjitske; Nadif Kasri, Nael; Schubert, Dirk (Journal article; Peer reviewed, 2022)
Heterozygous loss-of-function (LoF) mutations in SETD1A, which encodes a subunit of histone H3 lysine 4 methyltransferase, cause a neurodevelopmental syndrome and increase the risk for schizophrenia. Using CRISPR-Cas9, we ...