• Adherence to the Healthy Nordic Food Index and the incidence of acute myocardial infarction and mortality among patients with stable angina pectoris 

      Puaschitz, Nathalie Genevieve; Assmus, Jörg; Strand, Elin; Karlsson, Therese; Vinknes, Kathrine; Lysne, Vegard; Drevon, Christian A; Tell, Grethe S.; Dierkes, Jutta; Nygård, Ottar (Peer reviewed; Journal article, 2018-08-08)
      Background: The Healthy Nordic Food Index (HNFI) has been associated with beneficial effects on markers of cardiovascular disease (CVD). Whether such effects are present among patients with established coronary heart disease ...
    • Assessment of Dietary Choline Intake, Contributing Food Items, and Associations with One-Carbon and Lipid Metabolites in Middle-Aged and Elderly Adults: The Hordaland Health Study 

      Van Parys, Anthea; Lysne, Vegard; Dierkes, Jutta; Nygård, Ottar Kjell; Øyen, Jannike; Vinknes, Kathrine Jørgensen; Karlsson, Therese; Haugsgjerd, Teresa Risan; Tell, Grethe S.; Ueland, Per Magne; Brække, Maria Sandvik (Journal article; Peer reviewed, 2022)
      Background: Choline is an essential nutrient for humans and is involved in various physiologic functions. Through its metabolite betaine, it is closely connected to the one-carbon metabolism, and the fat-soluble choline ...
    • The association between alcohol consumption and risk of hip fracture differs by age and gender in Cohort of Norway: a NOREPOS study 

      Søgaard, Anne-Johanne; Ranhoff, Anette Hylen; Meyer, Haakon E; Omsland, Tone Kristin; Nystad, Wenche; Tell, Grethe S.; Holvik, Kristin (Peer reviewed; Journal article, 2018-11)
      Summary: The association between alcohol consumption and hip fracture differed by gender: Men aged 30–59 years drinking frequently or 14+ gl/week had higher risk than moderate drinkers. No significant association was seen ...
    • Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging 

      Dugué, Pierre-Antoine; Hodge, Allison M.; Ulvik, Arve; Ueland, Per Magne; Midttun, Øyvind; Rinaldi, Sabina; MacInnis, Robert J.; Li, Sherly X.; Meyer, Klaus; Navionis, Anne-Sophie; Flicker, Leon; Severi, Gianluca; English, Dallas R.; Vineis, Paolo; Tell, Grethe S.; Southey, Melissa C.; Milne, Roger L.; Giles, Graham G. (Journal article; Peer reviewed, 2022)
      Background Inflammation is a key feature of aging. We aimed to (i) investigate the association of 34 blood markers potentially involved in inflammatory processes with age and mortality and (ii) develop a signature of ...
    • Associations between fish intake and the metabolic syndrome and its components among middle-aged men and women: the Hordaland Health Study 

      Karlsson, Therese; Rosendahl-Riise, Hanne; Dierkes, Jutta; Drevon, Christian A; Tell, Grethe S.; Nygård, Ottar (Peer reviewed; Journal article, 2017)
      In epidemiologic studies, the relationship between fish consumption and the metabolic syndrome (MetS) have been inconclusive and sex differences reported. The aim was to investigate associations between fish intake and the ...
    • Ceramide stearic to palmitic acid ratio predicts incident diabetes 

      Hilvo, Mika; Salonurmi, Tuire; Havulinna, Aki S.; Kauhanen, Dimple; Pedersen, Eva Ringdal; Tell, Grethe S.; Meyer, Klaus; Teeriniemi, Anna-Maria; Laatikainen, Tiina; Jousilahti, Pekka; Savolainen, Markku J.; Nygård, Ottar; Salomaa, Veikko; Laaksonen, Reijo (Peer reviewed; Journal article, 2018-03-15)
      Aims/hypothesis Ceramide lipids have a role in the development of insulin resistance, diabetes and risk of cardiovascular disease. Here we investigated four ceramides and their ratios to find the best predictors of incident ...
    • Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease 

      Bjørnestad, Espen Ø.; Olset, Hilde; Dhar, Indu; Løland, Kjetil Halvorsen; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Svardal, Asbjørn M.; Berge, Rolf K; Ueland, Per Magne; Tell, Grethe S.; Nilsen, Dennis W.T.; Jan E., Nordrehaug; Nygaard, Ellisif; Nygård, Ottar (Journal article; Peer reviewed, 2020)
      Background The carnitine precursor trimethyllysine (TML) is associated with progression of atherosclerosis, possibly through a relationship with trimethylamine-N-oxide (TMAO). Riboflavin is a cofactor in TMAO synthesis. ...
    • Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study 

      Anfinsen, Åslaug Matre; Rosendahl-Riise, Hanne; Nygård, Ottar Kjell; Tell, Grethe S.; Ueland, Per Magne; Ulvik, Arve; McCann, Adrian; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)
      Purpose Dietary intake may have pronounced effects on circulating biomarker concentrations. Therefore, the aim was to provide a descriptive overview of serum metabolite concentrations in relation to time since last meal, ...
    • Factors associated with increase in blood pressure and incident hypertension in early midlife: the Hordaland Health Study 

      Kringeland, Ester Anne; Tell, Grethe S.; Midtbø, Helga Bergljot; Haugsgjerd, Teresa Risan; Igland, Jannicke; Gerdts, Eva (Journal article; Peer reviewed, 2020)
      Purpose: We aimed to identify sex-specific factors associated with increase in blood pressure (BP) and incident hypertension in early midlife. Materials and methods: 2,008 women and 1,610 men aged 40-43 years were ...
    • Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight 

      Iurilli, Maria Laura Caminia; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor; Solomon, Bethlehem D.; Taddei, Cristina; Danaei, Goodarz; Di Cesare, Mariachiara; Stevens, Gretchen A.; Riley, Leanne M.; Savin, Stefan; Cowan, Melanie J.; Bovet, Pascal; Damasceno, Albertino Antonio Moura; Chirita-Emandi, Adela; Hayes, Alison J; Ikeda, Nayu; Jackson, Rod T.; Khang, Young-Ho; Laxmaiah, Avula; Liu, Jing; Miranda, J. Jaime; Saidi, Olfa; Sebert, Sylvain; Sorić, Maroje; Starc, Gregor; Gregg, Edward W.; Abarca-Gómez, Leandra; Abdeen, Ziad A.; Abdrakhmanova, Shynar; Ghaffar, Suhaila Abdul; Rahim, Hanan Abdul; Abu-Rmeileh, Niveen M.; Garba, Jamila Abubakar; Acosta-Cazares, Benjamin; Adams, Robert J.; Aekplakorn, Wichai; Afsana, Kaosar; Afzal, Shoaib; Agdeppa, Imelda A.; Aghazadeh-Attari, Javad; Aguilar-Salinas, Carlos A.; Agyemang, Charles; Ahmad, Mohamad Hasnan; Ahmad, Noor Ani; Ahmadi, Ali; Ahmadi, Naser; Hassan, Soheir; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ariansen, Inger Kristine Holtermann; Bergh, Ingunn Holden; Bjertness, Espen; Bjertness, Marius Bergsmark; Ekelund, Ulf; Graff-Iversen, Sidsel; Grøholt, Else Karin; Haugsgjerd, Teresa Risan; Janszky, Imre; Kolle, Elin; Krokstad, Steinar; Madar, Ahmed Ali; Mathiesen, Ellisiv B.; Meisfjord, Jørgen Rajan; Meyer, Haakon Eduard; Sen, Abhijit; Skodje, Gry Irene; Sørgjerd, Elin Pettersen; Sparboe-Nilsen, Bente; Steene-Johannessen, Jostein; Tarp, Jakob; Tell, Grethe S.; Torheim, Liv Elin; Wilsgaard, Tom (Journal article; Peer reviewed, 2021)
      From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated ...
    • High-normal blood pressure in midlife is a stronger risk factor for incident hypertension 26 years later in women than men: the Hordaland Health Study 

      Ohldieck, Annabel Eide; Kringeland, Ester Anne; Midtbø, Helga Bergljot; Tell, Grethe S.; Gerdts, Eva (Journal article; Peer reviewed, 2023)
      Purpose To identify modifiable risk factors in early midlife associated with incident hypertension 26 years later in women and men. Materials and methods We used data from 1025 women and 703 men in the community-based ...
    • Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study 

      Kringeland, Ester Anne; Gerdts, Eva; Ulvik, Arve; Tell, Grethe S.; Igland, Jannicke; Haugsgjerd, Teresa Risan; Ueland, Per Magne; Midtbø, Helga Bergljot (Journal article; Peer reviewed, 2022)
      Our aim was to test sex-specific associations of circulating markers of inflammation with blood pressure (BP) and incident hypertension in midlife. Participants in the Hordaland Health study (n = 3280, 56% women, mean age ...
    • Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging 

      Solvang, Stein-Erik Hafstad; Hodge, Allison; Watne, Leiv; Cabral-Marques, Otavio; Nordrehaug, Jan Erik; Giles, Graham G.; Dugué, Pierre-Antoine; Nygård, Ottar Kjell; Ueland, Per Magne; McCann, Adrian; Idland, Ane-Victoria; Midttun, Øivind; Ulvik, Arve; Halaas, Nathalie Bodd; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2022)
      The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking. We investigated tryptophan (Trp) and downstream kynurenine ...
    • Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia 

      Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019)
      Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ...
    • Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study 

      Rosendahl-Riise, Hanne; Sulo, Gerhard; Karlsson, Therese; Drevon, Christian A.; Dierkes, Jutta; Tell, Grethe S. (Peer reviewed; Journal article, 2018-07-06)
      Hip fractures have a high prevalence worldwide. Few studies have investigated whether fish consumption is associated with risk of hip fractures. The objective of the present study was to investigate the effect of fish ...
    • Plasma cystathionine and risk of incident stroke in patients with suspected stable angina pectoris 

      Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Ueland, Per Magne; Lysne, Vegard; Svenningsson, Mads Malm; Tell, Grethe S.; Nygård, Ottar (Peer reviewed; Journal article, 2018)
      Background: Cystathionine is an intermediate product in the transsulfuration pathway and formed during the B6‐dependent conversion of methionine to cysteine. Elevated plasma cystathionine has been related to atherosclerosis, ...
    • Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts 

      Hilvo, Mika; Dhar, Indu; Lääperi, Mitja; Lysne, Vegard; Sulo, Gerhard; Tell, Grethe S.; Jousilahti, Pekka; Nygård, Ottar Kjell; Brenner, Hermann; Schöttker, Ben; Laaksonen, Reijo (Journal article; Peer reviewed, 2022)
      Aims Low-density lipoprotein cholesterol (LDL-C) is an established causal driver of atherosclerotic cardiovascular disease (ASCVD), but its performance and age-dependency as a biomarker for incident events and mortality ...
    • Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris 

      Strand, Elin; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Olsen, Thomas; Bjørndal, Bodil; Karlsson, Therese; Dierkes, Jutta; Njølstad, Pål Rasmus; Mellgren, Gunnar; Tell, Grethe S.; Berge, Rolf Kristian; Svardal, Asbjørn M.; Nygård, Ottar (Peer reviewed; Journal article, 2017-02)
      Background: Excess levels of serum acylcarnitines, which are intermediate products in metabolism, have been observed in metabolic diseases such as type 2 diabetes mellitus. However, it is not known whether acylcarnitines ...
    • Stage 1 hypertension, sex, and acute coronary syndromes during midlife: the Hordaland Health Study 

      Kringeland, Ester Anne; Tell, Grethe S.; Midtbø, Helga Bergljot; Igland, Jannicke; Haugsgjerd, Teresa Risan; Gerdts, Eva (Journal article; Peer reviewed, 2022)
      Aims: Hypertension has been suggested as a stronger risk factor for acute coronary syndromes (ACS) in women than men. Whether this also applies to stage 1 hypertension [blood pressure (BP) 130–139/80–89 mmHg] is not ...
    • Systemic Cardiac Troponin T Associated With Incident Atrial Fibrillation Among Patients With Suspected Stable Angina Pectoris 

      Vavik, Vegard; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Solheim, Eivind; Aakre, Kristin Moberg; Tell, Grethe S.; Nygård, Ottar; Vikenes, Kjell (Journal article; Peer reviewed, 2020)
      Higher concentrations of cardiac troponin T are associated with coronary artery disease (CAD) and adverse cardiovascular prognosis. The relation with incident atrial fibrillation (AF) is less explored. We studied this ...