Browsing Department of Clinical Science by Author "Vahokoski, Juha"
Now showing items 1-6 of 6
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Durable immune responses after BNT162b2 vaccination in home-dwelling old adults
Hansen, Lena; Brokstad, Karl Albert; Bansal, Amit; Zhou, Fan; Bredholt, Geir; Onyango, Therese Bredholt; Sandnes, Helene Heitmann; Elyanow, Rebecca; Madsen, Anders; Trieu, Mai Chi; Sævik, Marianne; Søyland, Hanne; Olofsson, Jan Stefan; Vahokoski, Juha; Ertesvåg, Nina Urke; Fjelltveit, Elisabeth Berg; Shafiani, Shahin; Tøndel, Camilla; Chapman, Heidi; Kaplan, Ian; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2023)Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We comprehensively analyzed the durability of humoral and cellular immune responses after BNT162b2 vaccination and SARS-CoV-2 infection ... -
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia
Saghaug, Christina Skår; Gamlem, Astrid Leinebø; Hauge, Kirsti Brugrand; Vahokoski, Juha; Klotz, Christian; Aebischer, Toni; Langeland, Nina; Hanevik, Kurt (Journal article; Peer reviewed, 2023)The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dependent on its activation/inactivation within the cytoplasm. There are several activating enzymes, including pyruvate ... -
Impact of ageing on homologous and human-coronavirus-reactive antibodies after SARS-CoV-2 vaccination or infection
Zhou, Fan; Vahokoski, Juha; Øyen, Siri; Sævik, Marianne; Høyland, Hanne; Sandnes, Helene Heitmann; Madsen, Anders; Brokstad, Karl Albert; Mohn, Kristin Greve-Isdahl; Tøndel, Camilla; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2024)The endemic human coronaviruses (HCoVs) circulate worldwide yet remain understudied and unmitigated. The observation of elevated levels of HCoV reactive antibodies in COVID-19 patients highlights the urgent necessity of ... -
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern
Ertesvåg, Nina Urke; Xiao, Julie; Zhou, Fan; Ljostveit, Sonja; Sandnes, Helene Heitmann; Lartey, Sarah; Sævik, Marianne; Hansen, Lena; Madsen, Anders; Mohn, Kristin Greve-Isdahl; Fjelltveit, Elisabeth Berg; Olofsson, Jan Stefan; Tan, Tiong Kit; Rijal, Pramilia; Schimanski, Lisa; Øyen, Siri; Brokstad, Karl Albert; Dunachie, Susanna; Jämsén, Anni; James, William S.; Harding, Adam C.; Harvala, Heli; Nguyen, Dung; Roberts, David; Patel, Monika; Gopal, Robin; Zambon, Maria; Wei, Leiyan; Gilbert-Jaramillo, Javier; Knight, Michael L.; Vaughan-Jackson, Alun; Dupont, Maeva; Lamikanra, Abigail A.; Klennerman, Paul; Townsend, Alain; Tøndel, Camilla; Kuwelker, Kanika; Blomberg, Bjørn; Bredholt, Geir; Onyango, Therese Bredholt; Vahokoski, Juha; Bansal, Amit; Trieu, Mai Chi; Amdam, Håkon; Akselsen, Per Espen; Skorge, Trude Duelien; Okkenhaug, Liv Heiberg; Linchausen, Dagrun Waag; Langeland, Nina; Cox Brokstad, Rebecca Jane (Journal article; Peer reviewed, 2022)Background: Evaluation of susceptibility to emerging SARS-CoV-2 variants of concern (VOC) requires rapid screening tests for neutralising antibodies which provide protection. Methods: Firstly, we developed a receptor-binding ... -
SARS-CoV-2–Specific Neutralizing Antibody Responses in Norwegian Health Care Workers After the First Wave of COVID-19 Pandemic: A Prospective Cohort Study
Trieu, Mai Chi; Bansal, Amit; Madsen, Anders; Zhou, Fan; Sævik, Marianne; Vahokoski, Juha; Brokstad, Karl Albert; Krammer, Florian; Tøndel, Camilla; Mohn, Kristin Greve-Isdahl; Blomberg, Bjørn; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Background During the coronavirus disease 2019 (COVID-19) pandemic, many countries experienced infection in health care workers (HCW) due to overburdened health care systems. Whether infected HCW acquire protective immunity ... -
Three doses of Sars-CoV-2 mRNA vaccine in older adults result in similar antibody responses but reduced cellular cytokine responses relative to younger adults
Bredholt, Geir; Sævik, Marianne; Søyland, Hanne; Ueland, Thor; Zhou, Fan; Pathirana, Rishi Delan; Madsen, Anders; Vahokoski, Juha; Jalloh, Sarah Larteley Lartey; Halvorsen, Bente; Dahl, Tuva Børresdatter; Trieu, Mai Chi; Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert; Aukrust, Pål; Tøndel, Camilla; Langeland, Nina; Blomberg, Bjørn; Cox Brokstad, Rebecca Jane (Journal article; Peer reviewed, 2024)Objectives Booster COVID-19 vaccinations are used to protect the elderly, a group vulnerable to severe disease. We compared humoral and cellular immunity in older versus younger adults up to eight months after administering ...