Blar i Department of Clinical Science på tidsskrift "International Journal of Pharmaceutics"

Viser treff 1-2 av 2

    • A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect 

      Bjørnstad, Ronja; Reiten, Ingeborg Nerbø; Knudsen, Kaja Skålnes; Schjøtt, Jan Didrik; Herfindal, Lars (Journal article; Peer reviewed, 2022)
      Anthracyclines such as doxorubicin (Dox) are the preferred chemotherapeutics for several cancers. However, Dox-induced cardiotoxicity limits its therapeutic potential. Liposomal encapsulation of Dox has been used for ...

    • Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation 

      Gundersen, Edvin Tang; Førde, Jan-Lukas; Tislevoll, Benedicte Sjo; Leitch, Calum; Barratt, Gillian; Gjertsen, Bjørn Tore; Herfindal, Lars (Journal article; Peer reviewed, 2022)
      Treatment of acute myeloid leukaemia (AML) relies on decades-old drugs, and while recent years have seen some breakthroughs, AML is still characterised by poor prognosis and survival rate. Drug repurposing can expedite the ...