Blar i Department of Clinical Science på tidsskrift "PLoS Biology"
Viser treff 1-2 av 2
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Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck
(Journal article; Peer reviewed, 2021)Mitochondrial DNA (mtDNA) and plastid DNA (ptDNA) encode vital bioenergetic apparatus, and mutations in these organelle DNA (oDNA) molecules can be devastating. In the germline of several animals, a genetic “bottleneck” ... -
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets
(Journal article; Peer reviewed, 2022-08-03)Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian ...