Department of Clinical Science: Nye registreringer
Viser treff 61-80 av 2310
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The liver-heart axis in patients with severe obesity: the association between liver fibrosis and chronic myocardial injury may be explained by shared risk factors of cardiovascular disease
(Journal article; Peer reviewed, 2024)Background: Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would ... -
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study
(Journal article; Peer reviewed, 2023)Background Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency. Moreover, MMA-dependent reactions have been ... -
Dementia Researchers’ Inside Views on Research Networks and Alignment With Public Research Funding: A Qualitative Study
(Journal article; Peer reviewed, 2023)This study presents the dementia researchers views of research networks, and how the networks fit into their pursuit of research objectives and dementia research funding. We conducted 10 semi-structured interviews with 10 ... -
Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms
(Journal article; Peer reviewed, 2023)High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients ... -
Evaluation of the Rosa Chatbot Providing Genetic Information to Patients at Risk of Hereditary Breast and Ovarian Cancer: Qualitative Interview Study
(Journal article; Peer reviewed, 2023)Background: Genetic testing has become an integrated part of health care for patients with breast or ovarian cancer, and the increasing demand for genetic testing is accompanied by an increasing need for easy access to ... -
Epicardial adipose tissue volume, plaque vulnerability and myocardial ischemia in non-obstructive coronary artery disease
(Journal article; Peer reviewed, 2023)Background Epicardial adipose tissue (EAT) accumulation has been associated with inflammation, atherosclerosis and microvascular dysfunction. Whether increased EAT volume is associated with coronary plaque vulnerability ... -
Less, but not gone—gluten-free diet effects on fatigue in celiac disease: a prospective controlled study
(Journal article; Peer reviewed, 2023)Introduction: Fatigue is a frequent complaint in patients with celiac disease. A gluten-free diet is the only established treatment for celiac disease, but how this diet influences fatigue is uncertain. We aimed to investigate ... -
N-terminal pro-B-type natriuretic peptide for prediction of ventricular arrhythmias: Data from the SMASH study
(Journal article; Peer reviewed, 2023)Background Elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations predict heart failure (HF) and mortality, but whether NT-proBNP predicts ventricular arrhythmias (VA) is not clear. Hypothesis We ... -
Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro
(Journal article; Peer reviewed, 2023)The clinical and adverse effects of the therapeutic monoclonal antibodies (mAb) ocrelizumab, ofatumumab and rituximab in multiple sclerosis (MS) are presently subject to extensive study. While the two former are approved ... -
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
(Journal article; Peer reviewed, 2023)Background Impulsivity is a transdiagnostic feature linked to severe clinical expression and a potential target for psychopharmacological strategies. Biological underpinnings are largely unknown, but involvement of ... -
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
(Journal article; Peer reviewed, 2023)The International prognostic Index (IPI) is the most widely used clinical prediction model for diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone ... -
Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods
(Journal article; Peer reviewed, 2023)Calprotectin (S100A8/S100A9, MRP8/MRP14) is a major leukocyte protein found to be more sensitive than C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) as a marker of inflammation in patients with rheumatoid ... -
Procollagen type 1 N-terminal propeptide is associated with adverse outcome in acute chest pain of suspected coronary origin
(Journal article; Peer reviewed, 2023)Background: Extracellular matrix (ECM) is an integral player in the pathophysiology of a variety of cardiac diseases. Cardiac ECM is composed mainly of collagen, of which type 1 is the most abundant with procollagen type ... -
Ultraprosessert mat burde være et kostråd: JA
(Journal article, 2023) -
Changes in Plasma Pyruvate and TCA Cycle Metabolites upon Increased Hepatic Fatty Acid Oxidation and Ketogenesis in Male Wistar Rats
(Journal article; Peer reviewed, 2023)Altered hepatic mitochondrial fatty acid β-oxidation and associated tricarboxylic acid (TCA) cycle activity contributes to lifestyle-related diseases, and circulating biomarkers reflecting these changes could have disease ... -
Double-vs single-balloon catheter for induction of labor: Systematic review and individual participant data meta-analysis
(Journal article; Peer reviewed, 2023)Introduction Evidence comparing double-balloon vs single-balloon catheter for induction of labor is divided. We aim to compare the efficacy and safety of double-vs single-balloon catheters using individual participant ... -
Differential sensitivity of the 2020 revised comprehensive diagnostic criteria and the 2019 ACR/EULAR classification criteria across IgG4-related disease phenotypes: results from a Norwegian cohort
(Journal article; Peer reviewed, 2023)Background We investigated sensitivity of the 2020 Revised Comprehensive Diagnostic Criteria (RCD) and the 2019 ACR/EULAR classification criteria across the four identified IgG4-related disease (IgG4-RD) phenotypes: ... -
Organizational structures influencing timely recognition and acknowledgment of end-of-life in hospitals – A qualitative study of nurses' and doctors’ experiences
(Journal article; Peer reviewed, 2023)Purpose Healthcare personnel's timely recognition and acknowledgment of end-of-life (EOL) is fundamental for reducing futile treatment, enabling informed decisions regarding the last days or weeks of life, and focusing ... -
Visceral fat percentage for prediction of outcome in uterine cervical cancer
(Journal article; Peer reviewed, 2023)Objective The prognostic role of adiposity in uterine cervical cancer (CC) is largely unknown. Abdominal fat distribution may better reflect obesity than body mass index. This study aims to describe computed tomography ... -
The Zebrafish Larva as a Model System for Myeloid Malignancies
(Doctoral thesis, 2024-02-23)Myeloid kreft er ein ukontrollert deling av dei myeloide stamcellene som finst i beinmergen. Døme på myeloid kreft er akutt myeloid leukemi (AML) og myelodysplastisk syndrom. Desse kreftformane er vanlegast hjå eldre ...