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dc.contributor.authorWidnes, Sofia Frosten_US
dc.date.accessioned2013-11-08T14:48:52Z
dc.date.available2013-11-08T14:48:52Z
dc.date.issued2013-10-25eng
dc.identifier.isbn978-82-308-2383-5en_US
dc.identifier.urihttps://hdl.handle.net/1956/7521
dc.description.abstractBackground: Drug use in pregnancy is common and both pregnant women and their physicians are in need of appropriate information for decision-making regarding drug therapy. However, uncertainty about the risks of drug use in pregnancy could result in restrictive attitudes to prescribing medicines and to their use. Purpose: To examine attitudes of and needs for medicines information among pregnant women and physicians. Materials and methods: Four studies based on three different methods were included; I: a descriptive study comparing drug advice regarding pregnancy from two commonly used sources: the Norwegian Drug Information Centres (DICs, named RELIS) and the product monographs in Felleskatalogen (FK), II: a survey among physicians who consulted RELIS for information on patient-specific drug use during pregnancy, III: interviews of pregnant women with epilepsy (WWE) using antiepileptic drugs (AEDs), IV: a survey among women attending ultrasound examination in gestation weeks 17-19 and their respective general practitioners (GPs). Results: Commonly used sources of information differed in advice regarding drug use in pregnancy. RELIS was a valued service among physicians and most advice had a clinical impact on therapeutic decisions. Pregnant WWE were confident in using AEDs through communication with their neurologist, but were concerned about dose adjustments. Pregnant women had higher teratogenic risk perceptions and lower confidence in use of medicines compared to their GPs. Phrasing of information texts may have influenced teratogenic risk perceptions. Conclusions and further implications: Deciding whether or not to prescribe or use medicines in pregnancy may be influenced by teratogenic risk perceptions, phrasing of medicines information, differences in advice between sources of information and availability of patient-specific and producer-independent medicines information. Physicians should aim to tailor the information to the pregnant woman’s risk perception level and desire for information.en_US
dc.language.isoengeng
dc.publisherThe University of Bergeneng
dc.relation.haspartPaper I: Frost Widnes SK, Schjøtt J. Advice on drug safety in pregnancy: are there differences between commonly used sources of information? Drug Saf 2008; 31(9):799-806. The article is not available in BORA due to publisher restrictions. The published version is available at: <a href="http://dx.doi.org/10.2165/00002018-200831090-00008" target="blank">http://dx.doi.org/10.2165/00002018-200831090-00008</a>en_US
dc.relation.haspartPaper II: Frost Widnes SK, Schjøtt J. Drug use in pregnancy - physicians' evaluation of quality and clinical impact of drug information centres. Eur J Clin Pharmacol 2009; 65(3):303-8. The article is not available in BORA due to publisher restrictions. The published version is available at: <a href="http://dx.doi.org/10.1007/s00228-008-0593-4" target="blank">http://dx.doi.org/10.1007/s00228-008-0593-4</a>en_US
dc.relation.haspartPaper III: Widnes SF, Schjøtt J, Granas AG. Risk perception and medicines information needs in pregnant women with epilepsy – a qualitative study. Seizure 2012; 21(8): 597–602. The article is not available in BORA due to publisher restrictions. The published version is available at: <a href="http://dx.doi.org/10.1016/j.seizure.2012.06.007" target="blank">http://dx.doi.org/10.1016/j.seizure.2012.06.007</a>en_US
dc.relation.haspartPaper IV: Widnes SF, Schjøtt J, Eide GE, Granas AG. Teratogenic risk perception and confidence in use of medicines in pairs of pregnant women and general practitioners based on patient information leaflets. Drug Saf 2013; 36(6):481-9. The article is not available in BORA due to publisher restrictions. The published version is available at: <a href="http://dx.doi.org/10.1007/s40264-013-0035-9" target="blank">http://dx.doi.org/10.1007/s40264-013-0035-9</a>en_US
dc.titleDrug information in pregnancy. Attitudes and needs among pregnant women and physiciansen_US
dc.typeDoctoral thesis
dc.typePeer reviewed
dc.rights.holderCopyright the author. All rights reserved


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