Show simple item record

dc.contributor.authorSønnesyn, Hogneen_US
dc.contributor.authorDalen, Ingvilden_US
dc.contributor.authorAarsland, Dagen_US
dc.description.abstractAim: To study the course and prognostic implications of orthostatic hypotension (OH) in older individuals with mild-to-moderate dementia. Methods: Referrals to outpatient clinics specialising in old age psychiatry and geriatric medicine in the counties of Rogaland and Hordaland in western Norway with a first-time diagnosis of mild dementia were consecutively asked for inclusion. A total of 211 participants underwent a comprehensive baseline assessment with annual follow-ups. Patients with OH at both baseline and the 1-year follow-up were classified as having persistent OH. Outcome measures were the Mini-Mental State Examination (MMSE), the Clinical Dementia Rating sum of boxes (CDR-SB), and time to death. Results: From baseline to the 4-year follow-up, 30–45% of the participants had OH at each follow-up. In multivariable analysis, persistent OH was not significantly associated with either the longitudinal course of MMSE or CDR-SB scores or survival. Conclusions: OH was moderately prevalent over 4 years in older individuals with mild dementia, and persistent OH did not predict either cognitive or functional decline or survival.en_US
dc.relation.ispartof<a href="" target="blank">Frequency and prognostic implications of orthostatic hypotension and white matter hyperintensities in older people with mild dementia</a>eng
dc.rightsAttribution-NonCommercial CC BY-NCeng
dc.subjectOrthostatic hypotensioneng
dc.subjectSurvival analysiseng
dc.titlePersistence and Prognostic Implications of Orthostatic Hypotension in Older Individuals with Mild-to-Moderate Dementiaen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2014 S. Karger AG. This is an Open Access article licensed under the terms of the Creative Commons Attribution- NonCommercial 3.0 Unported license (CC BY-NC).
dc.source.journalDementia and geriatric cognitive disorders extra

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial CC BY-NC
Except where otherwise noted, this item's license is described as Attribution-NonCommercial CC BY-NC