Browsing Department of Chemistry by Title
Now showing items 116-135 of 545
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Data on pigments and long-chain fatty compounds identified in Dietzia sp. A14101 grown on simple and complex hydrocarbons
(Peer reviewed; Journal article, 2015-09)This data article provides: 1. An overview of tentatively identified long chain compounds in Dietzia sp. A14101 grown on simple and complex hydrocarbons; 2. Preliminary Identification of pigments in bacterial material ... -
Deep-learning based reconstruction of dynamic non-Cartesian fMRI: Application to silent imaging
(Master thesis, 2023-06-02) -
DENOPTIM: Software for Computational de Novo Design of Organic and Inorganic Molecules
(Journal article; Peer reviewed, 2019)A general-purpose software package, termed DE Novo OPTimization of In/organic Molecules (DENOPTIM), for de novo design and virtual screening of functional molecules is described. Molecules of any element and kind, including ... -
Design and Synthesis of Carbazole Derivatives as Novel Therapeutic Candidates Against Acute Myeloid Leukaemia
(Master thesis, 2023-11-20)Akutt myelogen leukemi (AML) er ein heterogen gruppe blodkreft, karakterisert ved ukontrollert vekst av celler i den myelogene celle linja. Denne sjukdomsgruppa er assosiert med låg overlevingsrate, særleg hos eldre pasientar ... -
Design and Synthesis of Ruthenium based Olefin Metathesis Catalysts
(Master thesis, 2010-06-01)The present Master thesis seeks to develop new unsymmetrical ruthenium-based olefin metathesis catalysts and therein a better understanding of olefin metathesis catalysis with unsymmetrical active complexes. Such catalysts ... -
Design and synthesis of the Gilteritinib-Thalidomide PROTAC-like bifunctional molecule
(Master thesis, 2023-06-03) -
Design and Synthesis of xCT Inhibitor Candidates
(Master thesis, 2022-08-15) -
Design of iron(ii) spin-crossover compounds using de novo artificial evolution with fitness-function based on DommiMOE's implementation of LFMM
(Master thesis, 2015-06-01)This is a software development adding DommiMOE as a fitness-provider to the de novo artificial intelligence internally called Denoptim. The software supports stochastic conformational search, molecular dynamics, geometry ... -
Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)
(Journal article, 2014)Structure–activity relationship studies of the cyclopentapeptide CXCR4 antagonists (cyclo(-l-/d-Arg1-Arg2-2-Nal3-Gly4-d-Tyr5-)) suggest that the l-/d-Arg1-Arg2-2-Nal3 tripeptide sequence contained within these cyclopentapeptides ... -
Desorption of sulfamethoxazole from polyamide 6 microplastics: Environmental factors, simulated gastrointestinal fluids, and desorption mechanisms
(Journal article; Peer reviewed, 2023)Microplastics (MPs) can enrich pollutants after being released into the environment, and the contaminants-loaded MPs are usually ingested by organisms, resulting in a potential dual biotoxic effect. In this paper, the ... -
"Det er vitenskapelig bevist at miljø er viktig" - En kvalitativ studie av hvordan ungdomsskoleelever bygger opp argumenter
(Master thesis, 2020-06-27)Argumentasjon og kritisk tenkning trekkes frem som to viktige begreper i den nye læreplanen. Dette er en av årsakene til at jeg i denne masteroppgaven har ønsket å studere hvordan elever bygger opp argumenter. Den overordnede ... -
Determining the Cell Size of Yeast Using Diffusion-Weighted NMR
(Master thesis, 2019-11-16)Abstract This study uses diffusion weighted NMR to determine yeast cell size at different times after those cells were suspended in water. Both the water diffusion and the metabolite diffusion where used in those measurements. ... -
Development and optimisation of processes for active pharmaceutical ingredients:A modern approach to the synthesis of the potent anti-leukaemia drug -Quinacrine
(Master thesis, 2022-08-15)The extensive testing and approval needed before a new active pharmaceutical can be used in treatments of patients has lead to an increased interest in drug repurposing of older approved drugs as treatments for other ... -
Development and validation of a novel method for serotonin and 5-hydroxyindole-acetic acid determination in plasma using liquid chromatography tandem mass spectrometry
(Master thesis, 2014-05-07)5-Hydroxytryptamine (5-HT) also known as serotonin is a biomarker in gastrointestinal disorder and several other pathological diseases where 5-HT and its metabolite 5-hydroxyindole-acetic acid are implicated. A sensitive ... -
Development of a novel extraction method for the analysis of prostaglandins and leukotrienes in fish liver by using liquid chromatography mass spectrometry
(Master thesis, 2015-09-06)Eicosanoids are the major metabolites of fatty acids and they have pro-inflammatory anti-inflammatory proprieties, their role and production in solid biological tissue is important due to correlation with many kinds of ... -
Development of a solid phase extraction method for evaluating the production of classic and nonclassic eicosanoids in human and fish cells using liquid chromatography tandem mass spectrometry
(Master thesis, 2014-03-14)Eicosanoids are the major metabolites of fatty acids and they are correlated with many kinds of diseases such as Alzheimer's, cancer and cardiovascular diseases. Usually, most of the eicosanoids derived from omega-6 fatty ... -
Development of a System for Microdosimetric Assessment of Clinical Proton Treatment Plans via Proton Energy Spectra
(Master thesis, 2024-06-03)Purpose: The biological effectiveness of proton radiation depends on variables beyond the absorbed dose. In particular, the dose deposition on a micrometer scale may be relevant for subcellular structures such as DNA. ... -
Development of an extraction method for the analysis of pro-inflammatory prostaglandin-E2 and leukotriene-B4 in human plasma by liquid chromatography tandem mass spectrometry
(Master thesis, 2013-02-21)A simple and rapid method for extracting PGE2 and LTB4 from human plasma and further determination by LC-MS/MS proposed and validated. Extracting solvents, formic acid (10 µL) and acetonitrile (140 µL) were added subsequently ... -
Development of an imaging method for in vivo single-cell tracking under high-noise conditions: a proof of principle
(Journal article; Peer reviewed, 2023)This paper reports the development of a positron imaging method for in vivo single-cell tracking under high-noise conditions. Following biological processes spatially and temporally at a single-cell level in a living ... -
Development of Endothelial Barrier Models for Nanotoxicity Testing
(Master thesis, 2022-02-07)Nanotechnology is a field of both research and innovation that is ever-growing. It Is the study and manipulation of matter at the nanoscale to produce materials and devices with enhanced properties. Industries are spending ...