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dc.contributor.authorHanevik, Kurten_US
dc.contributor.authorDizdar, Vernesaen_US
dc.contributor.authorLangeland, Ninaen_US
dc.contributor.authorHausken, Trygveen_US
dc.description.abstractBackground: Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan Giardia lamblia. This study aims to characterize persistent abdominal symptoms elicited by Giardia infection according to Rome II criteria and symptoms scores. Methods: Structured interview and questionnaires 12–30 months after the onset of Giardia infection, and at least 6 months after Giardia eradication, among 82 patients with persisting abdominal symptoms elicited by the Giardia infection. All had been evaluated to exclude other causes. Results: We found that 66 (80.5%) of the 82 patients had symptoms consistent with irritable bowel syndrome (IBS) and 17 (24.3%) patients had functional dyspepsia (FD) according to Rome II criteria. IBS was sub classified into D-IBS (47.0%), A-IBS (45.5%) and C-IBS (7.6%). Bloating, diarrhoea and abdominal pain were reported to be most severe. Symptoms exacerbation related to specific foods were reported by 45 (57.7%) patients and to physical or mental stress by 34 (44.7%) patients. Conclusion: In the presence of an IBS-subtype pattern consistent with post-infectious IBS (PI-IBS), and in the absence of any other plausible causes, we conclude that acute Giardia infection may elicit functional gastrointestinal diseases with food and stress related symptoms similar to FGID patients in general.en_US
dc.publisherBioMed Centraleng
dc.relation.ispartof<a href="" target="_blank">Post-giardiasis functional gastrointestinal disorders and chronic fatigue syndrome – clinical symptoms, inflammation and immune responses</a>
dc.rightsAttribution CC BYeng
dc.titleDevelopment of functional gastrointestinal disorders after Giardia lamblia infectionen_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderCopyright 2009 Hanevik et al; licensee BioMed Central Ltd
dc.rights.holderKurt Hanevik et al.; licensee BioMed Central Ltd.
dc.source.journalBMC Gastroenterology

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