Faculty of Medicine: Nye registreringer
Viser treff 21-40 av 8759
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Key terms and definitions in acute porphyrias: Results of an international Delphi consensus led by the European porphyria network
(Journal article; Peer reviewed, 2023)Acute porphyrias are a group of rare inherited disorders causing acute neurovisceral attacks. Many terms used frequently in the literature and clinical practice are ambiguous, which can lead to confusion in the way patients ... -
External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)
(Journal article; Peer reviewed, 2023)Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ... -
Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial
(Journal article; Peer reviewed, 2024)Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ... -
The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients
(Journal article; Peer reviewed, 2023-06-26)Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus ... -
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions
(Journal article; Peer reviewed, 2023-02-02)Therapy of recurrent glioblastoma (GBM) is challenging due to lack of standard treatment. We investigated physicians’ treatment choice at recurrence and prognostic and predictive factors for survival in GBM patients from ... -
The surveillance of patients hospitalised with COVID-19 in Norway, February 2020 – May 2022 : Systems comparisons, risk factors and clinical course
(Doctoral thesis, 2024-04-26)Bakgrunn: I Norge ble tre ulike system for overvåking av pasienter innlagt i sykehus med COVID-19 opprettet for å overvåke alvorligheten av pandemien. Ett var en aggregert, manuell innrapportering om belegg ved sykehusene, ... -
SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients
(Journal article; Peer reviewed, 2023)Obesity is a known risk factor for severe respiratory tract infections. In this prospective study, we assessed the impact of being obese or overweight on longitudinal SARS-CoV-2 humoral and cellular responses up to 18 ... -
Novel Insights into the Pathogenesis of Human Post-Primary Tuberculosis from Archival Material of the Pre-Antibiotic Era, 1931–1947
(Journal article; Peer reviewed, 2023)Objectives: Primary and post-primary tuberculosis (TB) are distinct entities. The aim of this study was to study the histopathology of primary and post-primary TB by using the unique human autopsy material from the ... -
Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer
(Journal article; Peer reviewed, 2023)Active angiogenesis may be assessed by immunohistochemistry using Nestin, a marker of newly formed vessels, combined with Ki67 for proliferating cells. Here, we studied microvascular proliferation by Nestin-Ki67 co-expression ... -
Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: a nationwide registry study
(Journal article; Peer reviewed, 2023) -
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
(Journal article; Peer reviewed, 2023)Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ... -
TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma
(Journal article; Peer reviewed, 2024)Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ... -
Benzene exposure and risk of lung cancer in the Norwegian Offshore Petroleum Worker cohort: a prospective case-cohort study
(Journal article; Peer reviewed, 2024)Objective The objective of our study was to examine whether occupational exposure to benzene is associated with lung cancer among males in the Norwegian Offshore Petroleum Workers cohort. Methods Among 25 347 male offshore ... -
The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
(Journal article; Peer reviewed, 2023)The placenta plays a role in fetal brain development, and pregnancy and birth complications can be signs of placental dysfunction. Birth asphyxia is associated with smaller head size and higher risk of developing schizophrenia ... -
Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study
(Journal article; Peer reviewed, 2024)Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ... -
Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study
(Journal article; Peer reviewed, 2023-10-17)Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ... -
Targeted proteomics in a population-based study identifies serum PECAM-1 and TRIM21 as inflammation markers for periodontitis
(Journal article; Peer reviewed, 2023)Objectives Periodontitis (PD) can cause systematic inflammation and is associated with various metabolic processes in the body. However, robust serum markers for these relationships are still lacking. This study aims ... -
Real-world data on niraparib maintenance treatment in patients with non-gBRCA mutated platinum-sensitive recurrent ovarian cancer
(Journal article; Peer reviewed, 2023)Objectives The aim of this study was to provide real-world efficacy and safety data on niraparib maintenance treatment in patients with non-germline (gBRCA)1/2 mutated platinum-sensitive recurrent ovarian cancer. Methods ... -
A new pathway for penicillin delabeling in Norway
(Journal article; Peer reviewed, 2023)Background: Penicillin allergy is self-reported by 3–10% of patients admitted to hospital. The label is wrong in 90% of the cases and has severe health implications. Penicillin-delabeling can reverse the negative effects ... -
Evaluation of an interprofessional follow-up intervention among people with type 2 diabetes in primary care—A randomized controlled trial with embedded qualitative interviews
(Journal article; Peer reviewed, 2023)With an ageing population and improved treatments people live longer with their chronic diseases, and primary care clinics face more costly and difficult-to-treat multimorbid patients. To meet these challenges, current ...