Blar i Department of Clinical Medicine på forfatter "Dalen, Ingvild"
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Ankle fractures: a systematic review of patient‑reported outcome measures and their measurement properties
Nguyen, Michael Quan; Dalen, Ingvild; Iversen, Marjolein Memelink; Harboe, Knut; Paulsen, Aksel (Journal article; Peer reviewed, 2022)Purpose Ankle fractures are commonly occurring fractures, especially in the aging population, where they often present as fragility fractures. The disease burden and economic costs to the patient and society are considerable. ... -
Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease
Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Dalen, Ingvild; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2022)Background and Objectives Variations in the glucocerebrosidase gene (GBA) are common risk factors for Parkinson disease (PD) and dementia in PD (PDD) and cause a reduction in the activity of the lysosomal enzyme ... -
Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease
Grødem, Jodi Maple; Dalen, Ingvild; Tysnes, Ole-Bjørn; Macleod, Angus D.; Forsgren, Lars; Counsell, Carl E.; Alves, Guido Werner (Journal article; Peer reviewed, 2021)Objective To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). Methods Three European population-based ... -
Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study
Jacobsen, Cecilie; Zivadinov, Robert; Myhr, Kjell-Morten; Dalaker, Turi Olene; Dalen, Ingvild; Benedict, Ralph H.B.; Bergsland, Niels; Farbu, Elisabeth (Journal article; Peer reviewed, 2021)Objectives To identify Magnetic Resonance Imaging (MRI), clinical and demographic biomarkers predictive of worsening information processing speed (IPS) as measured by Symbol Digit Modalities Test (SDMT). Methods Demographic, ... -
Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study
Jacobsen, Cecilie; Zivadinov, Robert; Myhr, Kjell-Morten; Dalaker, Turi Olene; Dalen, Ingvild; Bergsland, Niels; Farbu, Elisabeth (Journal article; Peer reviewed, 2020)Background: Multiple sclerosis is often associated with unemployment. The contribution of grey matter atrophy to unemployment is unclear. Objectives: To identify magnetic resonance imaging biomarkers of grey matter and ... -
Cancer-related fatigue and treatment burden in surgically treated colorectal cancer patients – A cross-sectional study
Husebø, Anne Marie Lunde; Dalen, Ingvild; Søreide, Jon Arne; Bru, Edvin; Richardson, Alison (Journal article; Peer reviewed, 2021)Objective This cross-sectional study aimed to describe cancer-related fatigue (CRF) in colorectal cancer (CRC) patients who were surgically treated with curative intent, identify subgroups at risk of elevated fatigue ... -
Combinatory microRNA serum signatures as classifiers of Parkinson's disease
Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Peer reviewed; Journal article, 2019)Introduction: As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will ... -
CSF neurofilament light chain predicts 10-year clinical and radiologic worsening in multiple sclerosis
Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Bergsland, Niels; Zivadinov, Robert; Alves, Guido Werner; Myhr, Kjell-Morten; Farbu, Elisabeth (Journal article; Peer reviewed, 2021)Background Neurofilament light chain (NfL) is an attractive biomarker of disease activity and progression in MS, but there is a lack in long-term prognostic data. Objective To test the long-term clinical and radiological ... -
Data entry quality of double data entry vs automated form processing technologies: A cohort study validation of optical mark recognition and intelligent character recognition in a clinical setting
Paulsen, Aksel; Harboe, Knut; Dalen, Ingvild (Journal article; Peer reviewed, 2020)Background and Aims Patient-reported outcome measures (PROMs) are increasingly used in health services. Paper forms are still often used to register such data. Manual double data entry (DDE) has been defined as the gold ... -
Factors influencing treatment burden in colorectal cancer patients undergoing curative surgery: A cross-sectional study
Husebø, Anne Marie Lunde; Dalen, Ingvild; Søreide, Jon Arne; Bru, Lars Edvin; Richardson, Alison (Journal article; Peer reviewed, 2021)Objective To describe the severity of treatment burden in surgically treated colorectal cancer (CRC) patients and examine associations between treatment burden and demographic and clinical variables. Methods This ... -
GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study
Szwedo, Aleksandra Anna; Dalen, Ingvild; Pedersen, Kenn Freddy; Camacho, Marta; Bäckström, David; Forsgren, Lars; Tzoulis, Charalampos; Winder-Rhodes, Sophie; Hudson, Gavin; Liu, Ganqiang; Scherzer, Clemens R.; Lawson, Rachael A.; Yarnall, Alison J.; Williams-Gray, Caroline H.; Macleod, Angus D.; Counsell, Carl E.; Tysnes, Ole-Bjørn; Alves, Guido Werner; Maple-Grødem, Jodi (Journal article; Peer reviewed, 2022)Background: Common genetic variance in apolipoprotein E (APOE), β-glucocerebrosidase (GBA), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) has been linked to cognitive decline in Parkinson's disease (PD), ... -
Health promotion intervention for people with early-stage dementia: A quasi-experimental study
Testad, Ingelin; Kajander, Martine; Gjestsen, Martha Therese; Dalen, Ingvild (Journal article; Peer reviewed, 2020)Introduction: With the limited advancements in medical treatment, there is a growing need for supporting people with early‐stage dementia adjust to their diagnosis and improve their quality of life. This study aimed to ... -
Incidence and risk factors of intraoperative periprosthetic femoral fractures during primary total hip arthroplasty: 218,423 cases reported to the Norwegian Arthroplasty Register between 1987 and 2020
Brüggemann, Heinrich; Dalen, Ingvild; Bache-Mathiesen, Lena Kristin; Fenstad, Anne Marie; Hallan, Geir; Fosse, Lars (Journal article; Peer reviewed, 2022)Background and purpose: Intraoperative periprosthetic femoral fractures (IPFFs) can occur during primary total hip arthroplasty (THA). We describe the incidence of IPFFs during THA in Norway and estimate potential risk ... -
Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson’s Disease Cohorts
Grødem, Jodi Maple; Paul, Kimberly C.; Dalen, Ingvild; Ngo, Kathie J.; Wong, Darice; Macleod, Angus D.; Counsell, Carl E.; Bäckström, David; Forsgren, Lars; Tysnes, Ole-Bjørn; Kusters, Cynthia D.J.; Fogel, Brent L.; Bronstein, Jeff M.; Ritz, Beate; Alves, Guido Werner (Journal article; Peer reviewed, 2021)Background: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson’s disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on ... -
Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study
Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Alves, Guido Werner; Bergsland, Niels; Myhr, Kjell-Morten; Zetterberg, Henrik; Zivadinov, Robert; Farbu, Elisabeth (Journal article; Peer reviewed, 2023)Introduction. Cognitive impairment is an important contributor to disability in multiple sclerosis (MS). Disconnection of neuronal circuits due to axonal injury is probably an important underlying mechanism for this ... -
A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia
Aarsland, Dag; Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Holteng, Lise Birgitte Austbø; Oesterhus, Ragnhild; Nakling, Arne; Jarholm, Jonas Alexander; de Lucia, Chiara; Fladby, Tormod; Brooker, Helen; Dalen, Ingvild; Ballard, Clive (Journal article; Peer reviewed, 2023)Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ... -
Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder
Mangrud, Målfrid Ok; Waalen, Rune; Gudlaugsson, Einar; Dalen, Ingvild; Tasdemir, Ilker; Janssen, Emilius Adrianus Maria; Baak, Jan P.A. (Peer reviewed; Journal article, 2014-01-07)Background: European treatment guidelines of TaT1 urinary bladder urothelial carcinomas depend highly on stage and WHO1973-grade but grading reproducibility is wanting. The newer WHO2004 grading system is still debated and ... -
Self-management and HeAlth Promotion in Early-stage dementia with e-learning for carers (SHAPE): study protocol for a multi-centre randomised controlled trial
Testad, Ingelin; Clare, Linda; Anstey, Kaarin; Selbæk, Geir; Björklöf, Guro Hanevold; Henderson, Catherine; Dalen, Ingvild; Gjestsen, Martha Therese; Rhodes, Shelley; Røsvik, Janne-Kathrin; Bollen, Jessica; Amos, Jessica; Kajander, Martine; Quinn, Lynne; Knapp, Martin (Journal article; Peer reviewed, 2020)Background: With an increasing number of people with dementia worldwide and limited advancement in medical treatments, the call for new and cost-effective approaches is crucial. The utility of self-management has been ... -
Simulation-based team-training in acute stroke: Is it safe to speed up?
Høllesli, Liv Jorunn; Ajmi, Soffien Chadli; Kurz, Friedrich Martin Wilhelm; Tysland, Thomas Bailey; Hagir, Morten; Dalen, Ingvild; Qvindesland, Sigrun Anna; Ersdal, Hege Langli; Kurz, Kathinka Dæhli (Journal article; Peer reviewed, 2022)Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation-based team-training of the stroke treatment team was implemented, ... -
Triaging HPV-Positive Cervical Samples with p16 and Ki-67 Dual Stained Cytology within an Organized Screening Program—A Prospective Observational Study from Western Norway
Øvestad, Irene Tveiterås; Dalen, Ingvild; Andersland, Marie Songstad; Vintermyr, Olav Karsten; Moltu, Pia; Berland, Jannicke; Janssen, Emiel; Haugland, Hans Kristian (Journal article; Peer reviewed, 2023)The implementation of high-risk human papillomavirus testing (hrHPV testing) as a screening method in substitute for cytology has evoked the need for more sensitive and less objective tests for the triage of HPV-positive ...