Browsing Department of Clinical Medicine by Subject "IgA nephropathy"

Now showing items 1-2 of 2

Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

Paunas, Flavia Teodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Osman, Tarig Al-Hadi; Marti, Hans-Peter; Berven, Frode; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2019-11-14)

Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. Methods In ...
Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

Paunas, Flavia Teodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Marti, Hans-Peter; Mollnes, Tom Eirik; Berven, Frode; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2017-08-14)

Background: The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins associates with ...