Browsing Department of Clinical Medicine by Subject "Biomarkers"
Now showing items 1-4 of 4
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Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
(Peer reviewed; Journal article, 2019-05)Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ... -
Densities of rectal peptide YY and somatostatin cells as biomarkers for the diagnosis of irritable bowel syndrome
(Peer reviewed; Journal article, 2015-03-09)Irritable bowel syndrome (IBS) is a common chronic disorder. IBS diagnosis is a diagnosis of exclusion since there are no blood tests, radiological or endoscopic examinations for this disorder. Although several attempts ... -
Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
(Peer reviewed; Journal article, 2017-09-05)Background: Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested as a marker ... -
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
(Peer reviewed; Journal article, 2019-07-31)Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca ...