• CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration 

      Kråkenes, Torbjørn; Herdlevær, Ida Ajvazi; Raspotnig, Margrethe; Haugen, Mette; Schubert, Manja; Vedeler, Christian A. (Peer reviewed; Journal article, 2019)
      The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ...
    • Molecular pathogenesis of polymerase gamma-related neurodegeneration 

      Tzoulis, Charalampos; Tran, Gia Tuong Thi; Coxhead, Jonathan; Bertelsen, Bjørn; Lilleng, Peer Kåre; Balafkan, Novin; Payne, Brendan; Miletic, Hrvoje; Chinnery, Patrick F.; Bindoff, Laurence (Peer reviewed; Journal article, 2014-07)
      Objective: Polymerase gamma (POLG) mutations are a common cause of mitochondrial disease and have also been linked to neurodegeneration and aging. We studied the molecular mechanisms underlying POLG-related neurodegeneration ...