Browsing Department of Clinical Medicine by Subject "Cancer"
Now showing items 1-11 of 11
-
Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis
(Peer reviewed; Journal article, 2016-06-29)Background: More accurate predictive and prognostic biomarkers for patients with colorectal cancer (CRC) primaries or colorectal liver metastasis (CLM) are needed. Outside clinical trials, the translational integration of ... -
The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
(Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
(Peer reviewed; Journal article, 2019-05)Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ... -
Cancer-Associated stroke: The Bergen NORSTROKE Study
(Peer reviewed; Journal article, 2015-10-13)Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of ... -
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
(Peer reviewed; Journal article, 2017-05-19)Background: Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously ... -
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
(Peer reviewed; Journal article, 2015)Background: Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was ... -
Factors Associated with Altered Resting Energy Expenditure in Patients with Incurable Cancer
(Master thesis, 2024-05-15)Background and aim: There are indications that patients with cancer experience alterations in resting energy expenditure (REE) due to metabolic changes. Nutrition therapy is an integral part of palliative care, and alterations ... -
Global inequities in precision medicine and molecular cancer research
(Peer reviewed; Journal article, 2018-09-04)Precision medicine based upon molecular testing is heralded as a revolution in how cancer is prevented, diagnosed, and treated. Large efforts across the world aim to conduct comprehensive molecular profiling of disease to ... -
Nutrition Education as Part of a Cancer Rehabilitation Program: Evaluation of Short Term Efficacy
(Master thesis, 2018-06-22)Background and aim: The rising number of cancer patients is being followed by increasing number of cancer survivors in Norway. Modifiable lifestyle factors such as changing dietary behaviour can benefit the cancer prognosis ... -
Risk factors, complications and survival after upper abdominal surgery: A prospective cohort study
(Peer reviewed; Journal article, 2015-07-07)Background: Preoperative weight loss and abnormal serum-albumin have traditionally been associated with reduced survival. More recently, a correlation between postoperative complications and reduced long-term survival has ... -
Using patient-reported outcome measures for improved decision-making in patients with gastrointestinal cancer – the last clinical frontier in surgical oncology?
(Peer reviewed; Journal article, 2013-06-14)The genomic era has introduced concepts of “personalized medicine” and “targeted therapy” in the field of oncology. Medicine has become increasingly complex with a plethora of potential dilemmas in diagnosis, treatment, ...