Browsing Faculty of Medicine by Title
Now showing items 7407-7426 of 8849
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Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
(Journal article; Peer reviewed, 2020-06-04)Alpha defensins are anti-microbial peptides of the innate immune system. The defensin A1 and A3 genes are located in a repeat array of variable copy number (the DEFA1A3 locus) and encode the human neutrophil peptides 1, 2 ... -
Rural general practice staff experiences of patient safety incidents and low quality of care in Norway: an interview study
(Journal article; Peer reviewed, 2022)Background and objectives General practitioners (GPs), nurses and medical secretaries (practice staff) are responsible for the continuous provision of safe care in rural general practice. Little is known about their role ... -
Rural-urban differentials in pregnancy-related mortality in Zambia: estimates using data collected in a census
(Peer reviewed; Journal article, 2015-11-30)Background: The use of census data to measure maternal mortality is a recent phenomenon, implemented in settings with non-functional vital registration systems and driven by needs for trend data. The 2010 round of population ... -
Rural-urban inequity in unmet obstetric needs and functionality of emergency obstetric care services in a Zambian district
(Peer reviewed; Journal article, 2016-01-29)Background: Zambia has a high maternal mortality ratio, 398/100,000 live births. Few pregnant women access emergency obstetric care services to handle complications at childbirth. We aimed to assess the deficit in life-saving ... -
RvE1 Impacts the Gingival Inflammatory Infiltrate by Inhibiting the T Cell Response in Experimental Periodontitis
(Journal article; Peer reviewed, 2021)Periodontitis is a chronic inflammatory disease associated with the formation of dysbiotic plaque biofilms and characterized by the progressive destruction of the alveolar bone. The transition from health to disease is ... -
S100 proteins in acute myeloid leukemia
(Peer reviewed; Journal article, 2018-12)The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription ... -
S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
(Peer reviewed; Journal article, 2015-09-09)Background: Altered expression of S100A16 has been reported in human cancers, but its biological role in tumorigenesis is not fully understood. This study aimed to investigate the clinical significance and functional role ... -
Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis
(Journal article; Peer reviewed, 2022-05-30)Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ... -
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
(Journal article; Peer reviewed, 2012)Purpose: To evaluate the efficacy and safety of epithelium-on corneal collagen cross-linking (CXL) using a multifactorial approach to achieve proper stromal riboflavin saturation. Methods: This non-randomized retrospective ... -
Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: Study protocol for the randomised controlled phase II ReSScue trial
(Journal article; Peer reviewed, 2021)Introduction: In the multisystem inflammatory disorder systemic sclerosis (SSc), gastrointestinal tract (GIT) affliction is highly prevalent. There are no known disease modifying therapies and the negative impact is ... -
Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study
(Journal article; Peer reviewed, 2023)Background Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods BRIDGE is a phase 3 open-label, ... -
Safety and efficacy of rituximab as first- and second line treatment in multiple sclerosis – A cohort study
(Journal article; Peer reviewed, 2021-01-31)Background Rituximab is increasingly used as off-label therapy in multiple sclerosis (MS). More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo patients and patients in early therapy ... -
The safety attitudes questionnaire - Ambulatory version: Psychometric properties of the Norwegian translated version for the primary care setting
(Peer reviewed; Journal article, 2014-04-29)Background: Patient safety culture is how leader and staff interaction, attitudes, routines and practices protect patients from adverse events in healthcare. The Safety Attitudes Questionnaire is the most widely used ... -
The safety attitudes questionnaire - ambulatory version: psychometric properties of the Norwegian translated version for the primary care setting
(Peer reviewed; Journal article, 2014-03-29)Background: Patient safety culture is how leader and staff interaction, attitudes, routines and practices protect patients from adverse events in healthcare. The Safety Attitudes Questionnaire is the most widely used ... -
The safety attitudes questionnaire – ambulatory version: psychometric properties of the Norwegian version for nursing homes
(Peer reviewed; Journal article, 2019)Background: Patient safety culture involves leader and staff interaction, routines, attitudes, practices and awareness that influence risks of adverse events in patient care. The Safety Attitudes Questionnaire (SAQ) is an ... -
Safety measures to prevent workplace violence in emergency primary care centres - a cross-sectional study
(Peer reviewed; Journal article, 2013-10-03)Background: Employees in emergency primary care centres (EPCC) have raised personal safety as an issue. Despite a high risk of experiencing workplace violence at EPCCs in Norway, knowledge regarding applied preventive ... -
Safety of breast feeding during rituximab treatment in multiple sclerosis
(Journal article; Peer reviewed, 2022)Background There are limited data on the safety of breast feeding during rituximab therapy. Our objective is to determine exposure from breast feeding and biological effects of rituximab in breastfed infants. Methods ... -
Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus
(Journal article; Peer reviewed, 2020)Clinical guidance is often sought when prescribing drugs for patients with primary mitochondrial disease. Theoretical considerations concerning drug safety in patients with mitochondrial disease may lead to unnecessary ... -
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
(Journal article; Peer reviewed, 2023)Anemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United ...